Nizatidine Pregnancy and Breastfeeding Warnings

Nizatidine is also known as: Axid, Axid AR, Axid Pulvules

Nizatidine Pregnancy Warnings

Nizatidine has been assigned to pregnancy category B by the FDA. Animal studies have revealed no evidence of impaired fertility or harm to the fetus. There are no controlled data in human pregnancy. Nizatidine should only be given during pregnancy when benefit outweighs risk.

Nizatidine Breastfeeding Warnings

Nizatidine is excreted into human milk in small amounts. In one study, less than 0.1% of the maternal dose was eliminated in milk over 12 hours. The manufacturer recommends that due to the growth depression seen in pups reared by lactating rats while receiving nizatidine, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

The secretion of nizatidine into breast milk was studied in three lactating women. Following administration of nizatidine 150 mg, either one time or every 12 hours for five doses, an average of 96 mcg of nizatidine was secreted into milk over 12 hours. This amount represents 0.064% of the maternal dose.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web1)