Minoxidil topical Pregnancy and Breast Feeding Warnings
Minoxidil topical is also known as: Rogaine, Rogaine Extra Strength, Rogaine Men's Extra Strength, Rogaine Women's, Ronoxidil
Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Minoxidil Solution while you are pregnant. It is not known if Minoxidil Solution is found in breast milk. Do not breast-feed while using Minoxidil Solution.
Minoxidil topical Pregnancy Warnings
Minoxidil topical has been assigned to pregnancy category C by the FDA. Animal studies using oral minoxidil have failed to reveal evidence of teratogenicity, but reduced conception rates and an increased incidence of fetal absorption have been observed in rabbits given 5 times the usual human oral dose. Minoxidil topical should not be administered to pregnant women.
Only four cases of exposure to oral minoxidil in human pregnancy have been reported. In two of these four cases, minoxidil was associated with congenital abnormalities, but the presence of severe hypertension and the use of other drugs, including an ACE inhibitor in one case, make implication of minoxidil as a teratogen or as the sole teratogen difficult. Hypertrichosis was markedly evident in one malformed infant and as the sole abnormality in the other. One infant, whose mother was taking oral minoxidil throughout gestation, showed no adverse effects.
Minoxidil topical Lactation Warnings
Minoxidil is excreted into breast milk. Because of the potential for adverse effects in nursing infants, minoxidil topical should not be used by nursing women.
Limited data from a single study of a woman who was taking oral minoxidil 7.5 mg daily reveals a maximum milk to maternal plasma concentration ratio of 1:3 at one hour after dosing. Minoxidil was also detected in the breast milk of a woman taking minoxidil orally 5 mg twice a day.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
