Miconazole topical Pregnancy and Breastfeeding Warnings
Miconazole topical is also known as: Aloe Vesta, Aloe Vesta 2 in 1 Antifungal, Azolen, Baza Antifungal, Desenex Antifungal Atheletes Foot Spray Liquid, Desenex Prescription Strength, Fungoid, Lotrimin AF Athlete's Foot Powder, Lotrimin AF Athlete's Foot Spray, Lotrimin AF Deodorant Powder Spray, Lotrimin AF Jock Itch Powder Spray, Micatin, Micon 7, Miranel AF, Mitrazol, Monistat, Monistat 1-Day Ovule Combination Pack, Monistat 1-Day or Night Combination Pack, Monistat 3-Day Combination Pack, Monistat 7-Day Combination Pack, Monistat-Derm, Secura Antifungal, Tetterine, Zeasorb-AF, Zeasorb-AF Lotion/Powder
Miconazole topical Pregnancy Warnings
Pregnancy predisposes patients to the development of vaginal candidiasis due to changes in the vaginal tract. Miconazole has been used in several clinical trials for the treatment of vaginal candidiasis, generally during the second and third trimester, without evidence of fetal harm. In a review of 229,101 deliveries to Michigan Medicaid patients, 7266 first-trimester exposures to miconazole and 31,503 exposures any time during pregnancy were recorded. A total of 304 birth defects were reported with first trimester exposure (273 expected) and included (observed/expected) 77/73 cardiovascular defects, 14/13 clefts, 3 spina bifida, 4/4 oral clefts, 22/15 polydactyly, 12/9 limb reductions, and 20/17 hypospadias (written communication, Franz Rosa, MD, Food and Drug Administration, 1994). These data do not support an association between first-trimester miconazole use and birth defects.
Miconazole has not officially been assigned to a pregnancy category by the FDA. In clinical trials, miconazole treatment of vaginal candidiasis has not been associated with fetal harm. Miconazole is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.
Miconazole topical Breastfeeding Warnings
There are no data on the excretion of miconazole into human milk.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.