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Metronidazole topical Pregnancy and Breastfeeding Warnings

Metronidazole topical is also known as: MetroCream, MetroGel, MetroGel-Vaginal, MetroLotion, Noritate, Rosadan, Rozex, Vandazole, Vitazol

Metronidazole topical Pregnancy Warnings

Metronidazole has been assigned to pregnancy category B by the FDA when used intravaginally or topically. Metronidazole crosses the placental barrier and enters fetal circulation rapidly. Animal studies have failed to reveal evidence of fetotoxicity or teratogenicity when metronidazole was administered orally. There are no controlled data in human pregnancy. Metronidazole topical is only recommended for use during pregnancy when benefit outweighs risk.

Metronidazole topical Breastfeeding Warnings

There are no data on the excretion of metronidazole into human milk following topical or intravaginal administration. Following oral administration, metronidazole is excreted into human milk in concentrations similar to those found in the plasma. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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