Mefenamic acid Pregnancy and Breastfeeding Warnings

Mefenamic acid is also known as: Ponstel

Mefenamic acid Pregnancy Warnings

Mefenamic acid has been assigned to pregnancy category C by the FDA. Animal studies have shown decreased fertility, delay in parturition, and a decreased rate of survival to weaning at doses 10 times the human dose. There are no controlled data in human pregnancy. Mefenamic acid is only recommended for use during pregnancy when benefit outweighs risk.

Because nonsteroidal anti-inflammatory drugs (NSAIDs) are known to cause premature closure of the ductus arteriosus, use of mefenamic acid during late pregnancy is not recommended.

Mefenamic acid Breastfeeding Warnings

Trace amounts of mefenamic acid are excreted into human milk. The manufacturer recommends that a decision be made whether to discontinue nursing or to discontinue mefenamic acid, taking into account the importance of the drug to the mother.

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