Imiquimod topical Pregnancy and Breast Feeding Warnings
Imiquimod topical is also known as: Aldara
Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imiquimod while you are pregnant. It is not known if Imiquimod is found in breast milk after topical use. If you are or will be breast-feeding while you use Imiquimod , check with your doctor. Discuss any possible risks to your baby.
Imiquimod topical Pregnancy Warnings
Imiquimod 5% topical cream has been assigned to pregnancy category C by the FDA. Animal studies have revealed fetal toxicities, in the presence of maternal toxicity, including fetal resorptions, decreased fetal body weights, delays in skeletal ossification, and bent limb bones following doses 577 times the MHRD (based on AUC comparisons). In this same dosage group two fetuses in one litter demonstrated exencephaly, protruding tongues, and low set ears. Animal studies have failed to reveal evidence of teratogenicity or embryofetal toxicity when administered in doses up to 98 times MHRD (based on AUC comparisons). There are no controlled data in human pregnancy. Imiquimod 5% topical cream is only recommended for use during pregnancy when benefit outweighs risk.
Imiquimod topical Lactation Warnings
There are no data on the excretion of imiquimod into human milk. The manufacturer recommends that caution be used when administering imiquimod to nursing women.
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