Gemtuzumab Pregnancy and Breastfeeding Warnings

Gemtuzumab is also known as: Mylotarg

Gemtuzumab Pregnancy Warnings

Gemtuzumab has been assigned to pregnancy category D. Animal studies have revealed evidence of dose related decreases in fetal weight and fetal skeletal ossification, increased embryo-fetal mortality, digital malformations, absence of the aortic arch, wavy ribs, anomalies of the long bones in the forelimb(s), misshapen scapula, absence of vertebral centrum, and fused sternebrae. There are no controlled data in human pregnancy. Gemtuzumab is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk. If gemtuzumab is to be used in pregnancy or if the patient becomes pregnant while receiving gemtuzumab therapy, it is recommended that the patient be consulted regarding the potential hazard to the fetus. Women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with gemtuzumab.

Gemtuzumab Breastfeeding Warnings

There are no data on the excretion of gemtuzumab into human milk. Because many drugs are excreted into human milk, and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web4)