Ethionamide Pregnancy and Breast Feeding Warnings

Ethionamide is also known as: Trecator, Trecator-SC

Overview

If you become pregnant, discuss with your doctor the benefits and risks of using Ethionamide during pregnancy. It is unknown if Ethionamide is excreted in breast milk. If you are or will be breast-feeding while you are using Ethionamide , check with your doctor or pharmacist to discuss the risks to your baby.

Ethionamide Pregnancy Warnings

Ethionamide has been assigned to pregnancy category C by the FDA. Animal studies with high doses have revealed evidence of teratogenicity. There are no controlled data in human pregnancy. Seven cases of birth defects have been reported (23 exposed infants) in one study. The manufacturer recommends that ethionamide not be used in women who are pregnant or likely to become pregnant, unless it is considered an essential part of the regimen. Guidelines published by the American Thoracic Society, Centers for Disease Control, and Infectious Diseases Society of America recommend that ethionamide be avoided during pregnancy.

Ethionamide Lactation Warnings

There are no data on the excretion of ethionamide into human milk. Due to its low molecular weight, excretion is expected. The manufacturer recommends that ethionamide be given to nursing mothers only if the benefits outweigh the risks. Breast-fed neonates should be monitored for adverse effects.

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