Estradiol / norgestimate Pregnancy and Breastfeeding Warnings

Estradiol / norgestimate is also known as: Ortho-Prefest, Prefest

Estradiol / norgestimate Pregnancy Warnings

Estrogens have been assigned to FDA pregnancy category X by the FDA. Estrogenic agents have been associated with urogenital abnormalities in offspring that manifest later in life. Vaginal adenosis, squamous cell dysplasia of the uterine cervix and vaginal cancer have developed later in life in female offspring. In male offspring, the risks of urogenital abnormalities and testicular cancer later in life are increased. Estrogens are contraindicated during pregnancy.

Estradiol / norgestimate Breastfeeding Warnings

Estradiol and progestins are excreted into human milk in small amounts. Estrogens have been shown to decrease the quantity and quality of breast milk. The manufacturer recommends that caution be used when administering estradiol-norgestimate to nursing women.

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