Dorzolamide ophthalmic Pregnancy and Breast Feeding Warnings
Dorzolamide ophthalmic is also known as: Trusopt
Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dorzolamide Drops while you are pregnant. It is not known if Dorzolamide Drops is found in breast milk. Do not breast-feed while taking Dorzolamide Drops.
Dorzolamide ophthalmic Pregnancy Warnings
Dorzolamide has been assigned to pregnancy category C by the FDA. Animal studies revealed evidence of malformations of the vertebral bodies in rabbits in oral doses of approximately 31 times the maximum recommended human ophthalmic dose. These malformations occurred at doses that caused metabolic acidosis with decreased maternal body weight and decreased fetal weight. Dorzolamide caused no malformations in rats given 125 times the recommended human ophthalmic dose. There are no controlled data in human pregnancy. Dorzolamide is only recommended for use during pregnancy when benefit outweighs risk.
Dorzolamide ophthalmic Lactation Warnings
There are no data on the excretion of dorzolamide into human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
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