Dinoprostone topical Pregnancy and Breastfeeding Warnings
Dinoprostone topical is also known as: Cervidil, Prepidil, Prostin E2
Dinoprostone topical Pregnancy Warnings
Dinoprostone topical has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of embryotoxicity, and any dose that produces sustained increased uterine tone could put the embryo or fetus at risk. Prostaglandin E2 has produced an increase in skeletal anomalies in rats and rabbits. No effects would be expected clinically, when used as indicated, since dinoprostone vaginal insert and cervical gel are administered after the period of organogenesis. Animal studies have failed to reveal evidence of teratogenicity with dinoprostone vaginal suppository. Dinoprostone topical is only recommended for use during pregnancy when benefit outweighs risk.
Dinoprostone topical Breastfeeding Warnings
There are no data on the excretion of dinoprostone topical into human milk.
See Also...
- Dinoprostone use while Breastfeeding (in more detail)
- dinoprostone gel Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
