Delavirdine Pregnancy and Breastfeeding Warnings

Delavirdine is also known as: Rescriptor

Delavirdine Pregnancy Warnings

Delavirdine has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of teratogenicity in rats at doses producing exposure equal to or less than the anticipated human exposure at the recommended dose. There are no controlled data in human pregnancy. Delavirdine should only be given during pregnancy when there are no alternatives and benefit outweighs risk.

Seven unplanned pregnancies were reported during premarketing clinical studies in patients who received delavirdine. Three resulted in ectopic pregnancies, three resulted in healthy live births, and one was born prematurely with a muscular ventricular septal defect. The mother of the latter infant received treatment with delavirdine and zidovudine for approximately 6 weeks early in the course of pregnancy. Descriptions of maternal exposure to delavirdine in the other cases were not reported. An Antiretroviral Pregnancy Registry has been established to monitor maternal:fetal outcome of delavirdine exposures during pregnancy. To register patients, physicians should call 1-800-258-4263.

Delavirdine Breastfeeding Warnings

There are no data on the excretion of delavirdine into human milk. HIV-infected mothers should not breast-feed their infants due to the risk of transmission of HIV via breast milk.

See Also...

• Delavirdine use while Breastfeeding (in more detail)
• delavirdine Consumer Information
• Pregnancy Support Group
• FDA Pregnancy Categories
• Medicine use during Pregnancy
• Medicine use while Breastfeeding
• Safe Medications during Breastfeeding

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.