Darbepoetin alfa Pregnancy and Breastfeeding Warnings

Darbepoetin alfa is also known as: Aranesp

Darbepoetin alfa Pregnancy Warnings

Darbepoetin alfa has been assigned to pregnancy category C by the FDA. Animal studies at doses up to 20 mcg/kg/day (40-fold higher than the initial recommended dose in humans) have failed to reveal evidence of embryotoxicity, fetotoxicity, or teratogenicity. A slight reduction in fetal weight was observed in animals that received doses of 1 mcg/kg/day or higher. Darbepoetin alfa is only recommended for use during pregnancy when benefit outweighs risk.

Darbepoetin alfa Breastfeeding Warnings

There are no data on the excretion of darbepoetin alfa into human milk. The manufacturer recommends that caution be used when administering darbopoetin alfa to nursing women.

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