Daptomycin Pregnancy and Breastfeeding Warnings
Daptomycin is also known as: Cubicin
Daptomycin Pregnancy Warnings
Daptomycin has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy. Daptomycin is only recommended for use during pregnancy when benefit outweighs risk.
Daptomycin Breastfeeding Warnings
In one case study, 6.7 mg/kg/day of intravenous daptomycin was administered to a nursing mother for 28 days. Samples of the patient's breast milk were collected over a 24-hour period on day 27. The highest daptomycin level measured in the breast milk was 0.045 mcg/mL. The calculated maximum daily daptomycin dose to the infant (assuming mean milk consumption of 150 mL/kg/day) was 0.1% of the maternal dose.
Daptomycin is excreted into human milk; however, it has poor oral bioavailability. The effects in the nursing infant are unknown. The manufacturer recommends that caution be used when administering daptomycin to nursing women.
See Also...
- Daptomycin use while Breastfeeding (in more detail)
- daptomycin Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
