Chlorpheniramine / methscopolamine / phenylephrine Pregnancy and Breastfeeding Warnings
Chlorpheniramine / methscopolamine / phenylephrine is also known as: Aerohist Plus, Ah-Chew Ultra Tannate, AlleRx Dose Pack (PM Dose), Allergy DN PE, CPM-PE-MSC, Dallergy PE, Dallergy SR, Dehistine, Denaze, DriHist SR, DuraTan PE, Duradryl Chewable, Duradryl SR, Duravent, Nohist PE, Nohist Plus, Nohist Plus Jr, PCM, Ralix, RelCof DN PE, RelCof PE, ScopoHist Syrup, ScopoHist-PE, SymPak PDX, Triall
Chlorpheniramine / methscopolamine / phenylephrine Pregnancy Warnings
Reproductive animal studies with chlorpheniramine demonstrated no harm to the fetus. Reproductive animal studies have not been reported with methscopolamine and phenylephrine. There are no controlled data in human pregnancy. The Collaborative Perinatal Project monitored 1,070 first trimester exposures and 3,931 exposures which occurred anytime during pregnancy. No evidence was found to suggest a relationship to large categories of malformations. Antihistamine exposure in the first trimester in general was not associated with an increased risk of malformations.
Chlorpheniramine/methscopolamine/phenylephrine has been assigned to pregnancy category C by the FDA. Chlorpheniramine/methscopolamine/phenylephrine is only recommended for use during pregnancy when benefit outweighs risk.
Chlorpheniramine / methscopolamine / phenylephrine Breastfeeding Warnings
Small amounts of sympathomimetic amines and antihistamines are excreted in breast milk and because of the risk of adverse reactions in nursing infants (excitement or irritability), use is not recommended. Anticholinergics and antihistamines may inhibit lactation.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.