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Cefotaxime Pregnancy and Breastfeeding Warnings

Cefotaxime is also known as: Claforan

Cefotaxime Pregnancy Warnings

Cefotaxime has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy. Cefotaxime should only be given during human pregnancy when need has been clearly established.

See references

Cefotaxime Breastfeeding Warnings

Cefotaxime is excreted into breast milk in small amounts. Cefotaxime is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that caution be used when administering cefotaxime to nursing women.

See references

References for pregnancy information

  1. "Product Information. Claforan (cefotaxime)." Hoechst Marion-Roussel Inc, Kansas City, MO.
  2. Czeizel AE, Rockenbauer M, Sorensen HT, Olsen J "Use of cephalosporins during pregnancy and in the presence of congenital abnormalities: A population-based, case-control study." Am J Obstet Gynecol 184 (2001): 1289-96

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  2. Kafetzis DA, Lazarides CV, Siafas CA, et al "Transfer of cefotaxime in human milk and from mother to foetus." J Antimicrob Chemother 6 (1980): 135-41
  3. "Product Information. Claforan (cefotaxime)." Hoechst Marion-Roussel Inc, Kansas City, MO.

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