Carisoprodol Pregnancy and Breastfeeding Warnings
Carisoprodol Pregnancy Warnings
Animal studies have reported reduced testes weight and sperm motility. The significance of these findings for human fertility is unknown.
Carisoprodol has been assigned to pregnancy category C by the FDA. Animal studies have reported that carisoprodol crosses the placenta and results in adverse effects on fetal growth and postnatal survival. However, animal studies have not adequately evaluated the teratogenic effects of carisoprodol. There are no controlled data in human pregnancy. Carisoprodol should only be given during pregnancy when benefit outweighs risk.
Carisoprodol Breastfeeding Warnings
Carisoprodol is excreted into human milk in concentrations two to four times that in the maternal plasma. Adverse effects in nursing infants have not been reported but are theoretically possible. Caution is recommended if carisoprodol is administered to a nursing woman.
In one case report, a breast-fed infant received about 4% to 6% of the maternal daily dose through breast milk and experienced no adverse effects. However, milk production was inadequate and the baby was supplemented with formula. In animal lactation studies, female offspring survival and offspring weight at weaning were decreased. This suggests that maternal use of carisoprodol may lead to reduced or less effective infant feeding (due to sedation) and/or decreased milk production.
- Carisoprodol use while Breastfeeding (in more detail)
- Carisoprodol Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.