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Carbidopa Pregnancy and Breastfeeding Warnings

Carbidopa is also known as: Lodosyn

Carbidopa Pregnancy Warnings

Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Although levodopa crosses the human placental barrier, enters the fetus, and is metabolized, it was reported that carbidopa concentrations were minimal in fetal tissue. AU TGA pregnancy category B3: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals have shown evidence of an increased occurrence of fetal damage, the significance of which is considered uncertain in humans. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus. AU TGA pregnancy category: B3 US FDA pregnancy category: C

Carbidopa Breastfeeding Warnings

A decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown The effects in the nursing infant are unknown.

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