Amantadine Pregnancy and Breast Feeding Warnings

Amantadine is also known as: Symmetrel

Overview

If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Amantadine Syrup while you are pregnant. Amantadine Syrup is found in breast milk. Do not breast-feed while taking Amantadine Syrup.

Amantadine Pregnancy Warnings

Amantadine has been assigned to pregnancy category C by the FDA. Some animal studies have revealed evidence of embryotoxicity and teratogenicity using doses 12 times the recommended human dose. There are no controlled data in human pregnancy. A cardiovascular birth defect (single ventricle with pulmonary atresia) was reported in an infant whose mother had taken 100 mg/day during the first 2 weeks of pregnancy. Tetralogy of Fallot and tibial hemimelia was reported in an infant whose mother took 100 mg/day for 1 week during the sixth and seventh week of pregnancy. Amantadine should only be given during pregnancy when benefit outweighs risk.

Amantadine Lactation Warnings

Amantadine is excreted into human milk in small amounts. Due to the potential for adverse effects, the use of amantadine while breast-feeding is not recommended.

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