Trypsin / Balsam Peru / Castor Oil

Trade Names:
Granulex
- Aerosol 0.12 mg trypsin/87 mg balsam peru/788 mg castor oil per g

Pharmacology

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Physiologically debrides tissue; improves epithelization by reducing premature epithelial desiccation and cornification.

Indications and Usage

In acute and chronic conditions such as varicose ulcers, decubital ulcers, eschar, dehiscent wounds and sunburn, relieves pain and promotes healing; debrides eschar and necrotic tissue; stimulates vascular bed; improves epithelization; reduces odor from necrotic wounds.

Contraindications

Standard considerations.

Dosage and Administration

Aerosol Shake well and hold upright approximately 12 inches from the area to be treated. Apply twice daily or as often as necessary. To remove, wash gently with water.

Storage/Stability

Store at controlled room temperature (less than 86°F). Do not expose can to temperatures above 120°F.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Dermatologic

Stinging or burning sensation; irritation.

Precautions

Arterial clots

Do not spray on fresh arterial clots.

External use only

Avoid spraying in eyes.

Flammable

Do not expose to fire or open flame.

Overdosage

Symptoms

Concentrating and inhaling the contents can be harmful or fatal.

Patient Information

• Advise patient, family, or caregiver that medication will usually be prepared and applied by a health care provider in a medical setting but may also be used in a home environment.
• Review prescribed dosing schedule and application process with patient, parent, or caregiver.
• Advise patient, parent, or caregiver that spray may produce a temporary stinging sensation when applied to sensitive skin, but that this should be tolerable. If it persists or is intolerable, notify health care provider.

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