- Tablets 12.5 mg
- Tablets 25 mg
- Tablets 50 mg
- Chewable Tablets 25 mg
Dramamine Less Drowsy
- Tablets 25 mg
Acts on CNS to decrease vestibular stimulation and depress labyrinthine activity.
The t ½ is 6 h.
Onset is 30 min to 1 h (oral).
Duration is 4 to 6 h (25 mg) and 12 to 24 h (30 mg).
Indications and Usage
Prevention and treatment of nausea, vomiting, and dizziness of motion sickness; possibly effective treatment for vertigo of vestibular dysfunction origin.
Hypersensitivity to cyclizine; asthma; glaucoma; emphysema; chronic pulmonary disease; shortness of breath; difficulty breathing; urinary retention caused by enlarged prostate.
Dosage and AdministrationMotion Sickness
PO 25 to 50 mg 1 h before travel; may repeat every 24 h during travel.Vertigo
PO 25 to 100 mg/day in divided doses.
Store between 59° and 86°F.
Drug InteractionsAlcohol, CNS depressants, sedatives, tranquilizers
Additive CNS effects. Avoid concomitant use with alcohol.
Laboratory Test Interactions
False-negative result in allergy skin testing.
Hypotension; tachycardia; palpitations.
Drowsiness; excitation; nervousness; restlessness; insomnia; euphoria; vertigo; hallucinations.
Dry nose and throat; visual disturbances; tinnitus.
Nausea; vomiting; dry mouth; diarrhea; constipation; anorexia.
Urinary frequency; urinary retention; difficulty urinating.
Category B .
Safety and efficacy not established. Not recommended in children younger than 12 y of age.
Special Risk Patients
Ask a health care provider before using in patients with glaucoma, trouble urinating due to an enlarged prostate gland, emphysema, and/or chronic bronchitis.
Hyperexcitability, drowsiness, hallucinations, convulsions.
- When given for motion sickness, inform patient that first dose should be taken 1 h before exposure to motion.
- Instruct patient to take sips of water frequently, suck on ice chips or sugarless hard candy or chew sugarless gum if dry mouth occurs.
- Explain that high-fiber diet and drinking plenty of fluids may help to prevent constipation, which is common adverse reaction.
- Instruct patient to report the following symptoms to health care provider: sedation, dizziness, palpitations, difficulty urinating, or urinary retention.
- Instruct patient to notify health care provider if vomiting increases or becomes severe.
- Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.
- Instruct patient to avoid intake of alcoholic beverages or other CNS depressants.
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