Dextromethorphan Hydrobromide / Benzocaine

Trade Names:
Cepacol Dual Relief
- Spray 5 mg dextromethorphan and 5% benzocaine

Trade Names:
Cepacol Ultra Sore Throat Plus Cough
- Spray 5 mg dextromethorphan and 7.5 mg benzocaine

Trade Names:
Tetra-Formula
- Lozenges 10 mg dextromethorphan and 15 mg benzocaine

Pharmacology

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Suppresses cough by central action on cough center in medulla.

Indications and Usage

Temporary relief of minor sore throat; temporary reduction in cough caused by minor throat and bronchial irritation.

Contraindications

MAOI therapy or for 2 wk after stopping MAOI therapy; allergy to local anesthetics (eg, butacaine, procaine) or any component of this product.

Dosage and Administration

PO 2 sprays every 4 h (max, 8 sprays/24 h).

PO 1 spray every 4 h (max, 4 sprays/24 h).

PO 1 lozenge every 2 h as needed (max, 12 lozenges/24 h), or as directed by health care provider.

PO 1 lozenge every 4 h (max, 6 lozenges/24 h), or as directed by health care provider.

PO Dissolve 1 lozenge slowly in the mouth, do not chew. May be repeated every 4 h or as directed by health care provider.

General Advice

• Cepacol Dual Relief
• Spray into throat and then swallow.

Storage/Stability

Store at 59° to 86°F. Protect from moisture. Do not freeze.

Drug Interactions

Dextromethorphan is contraindicated with MAOIs.

Laboratory Test Interactions

None well documented.

Adverse Reactions

CNS

Drowsiness; dizziness.

GI

Nausea.

Precautions

Pregnancy

Consult health care provider before use.

Lactation

Consult health care provider before use.

Children

Do not use Cepacol Dual Relief in children younger than 6 yr of age.

Chronic cough

Do not use in chronic cough such as occurs with smoking, emphysema, or asthma.

Excessive phlegm

Do not use with a cough that is accompanied by excessive phlegm.

Overdosage

Symptoms

Respiratory depression.

Patient Information

• Advise patient to take as directed on the package insert or as advised by their health care provider.
• Advise patient that if symptoms are not controlled not to increase the dose of medication or frequency of use but to inform their health care provider.
• Instruct patient to notify their health care provider if any of the following occur: cough persists for longer than 1 wk or tends to recur; severe sore throat persists for more than 2 days, or if cough or sore throat is accompanied by fever, persistent headache, rash, swelling, nausea, or vomiting.

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