Betamethasone / Clotrimazole
Pronouncation: (BAY-tuh-METH-uh-zone/kloe-TRIM-uh-zole)Class: Topical corticosteroid
Trade Names:
Lotrisone
- Cream 0.05% betamethasone (as dipropionate)/1% clotrimazole
Pharmacology
Feedback for Betamethasone/Clotrimazole
Compare with other drugs.
  |
Clotrimazole increases cell membrane permeability in susceptible fungi. Betamethasone has anti-inflammatory, antipruritic, and vasoconstrictive actions.
Indications and Usage
Topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum , T. mentagrophytes , Epidermophyton floccosum , Microsporum canis .
Contraindications
Hypersensitivity to other corticosteroids or imidazoles.
Dosage and Administration
Topical 1 application twice daily (2 wk for tinea cruris and tinea corporis; 4 wk for tinea pedis).
General Advice
- Wear gloves. Apply medication sparingly and rub in lightly. Notify health care provider if signs of hypersensitivity or irritation are noted.
- Avoid contact with eyes, mouth, and nose.
- Do not cover treated area with dressings or use tight-fitting diapers, plastic pants, or underwear over treated area.
Storage/Stability
Store cream at room temperature.
Drug Interactions
None well documented.
Laboratory Test Interactions
None well documented.
Adverse Reactions
CNS
Paresthesias.
Dermatologic
Maculopapular rash; erythema; stinging; blistering; peeling; pruritus; urticaria; burning; itching; dryness; acne; decreased pigmentation; striae; skin atrophy.
Miscellaneous
Edema; secondary infection; adrenal suppression with long-term use over large areas of skin.
Precautions
MonitorMonitor treated sites for irritation or signs of secondary infection, and report any adverse reactions to health care provider. |
Pregnancy
Category C .
Lactation
Undetermined.
Children
Safety and efficacy not established.
Adrenal suppression
Patients who receive large doses over large surface areas may experience HPA axis suppression.
Ophthalmic use
Do not use for eye infections.
Patient Information
- Remind patient that medication is for external application only and to avoid contact with eyes, nose, and mouth.
- Demonstrate application technique, cautioning patient to apply sparingly and to rub in lightly.
- Tell patient to notify health care provider if there is no improvement after 1 wk for tinea cruris or tinea corporis or after 2 wk for tinea pedis.
- Caution patient against using dressings, tight-fitting diapers, or plastic pants over treated area.
- Tell patients with tinea corporis (ringworm) to wash clothes separately from those of other family members.
- Remind patient to wash hands before and after each application of product.
- Advise patient to complete prescribed treatment, even if infection clears, to prevent relapse.
- Instruct patient to report the following symptoms to health care provider: burning, itching, rash, swelling, redness or blistering in treated area.
| Link to this page |  |
Printable Version |  |
Email Page |  |
Add to my drug list |
Tinea Corporis, Tinea Pedis, Tinea Cruris
