Antipyrine / Benzocaine

Pronunciation: an-tee-PYE-reen/BEN-zoe-kane
Class: Otic preparation

Trade Names

Aurax
- Solution, otic antipyrine 5.5%, benzocaine 1.4%, glycerin, oxyquinoline

Aurodex
- Solution, otic antipyrine 5.4% and benzocaine 1.4%

Neotic
- Solution, otic antipyrine 5.4%, benzocaine 1%, glycerin 2%, and zinc 1%

Otic Care
- Solution, otic antipyrine 5.4%, benzocaine 1.4%, polycosanol 0.0097%, acetic acid, aluminium acetate, glycerin

Otozin
- Solution, otic antipyrine 5.4%, benzocaine 1%, glycerin 2%, zinc 1%

Treagan
- Solution, otic antipyrine 5.4%, benzocaine 1.4%, polycosanol 0.0097%, acetic acid, glycerin

Pharmacology

Decongestant/analgesic/skin protectant

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Indications and Usage

Treatment of acute otitis media of various etiologies; removal of cerumen.

Contraindications

Perforated tympanic membrane or discharge; hypersensitivity to any of the components or related substances.

Dosage and Administration

Otic Instill solution to run along the wall of the ear canal until filled, then insert cotton pledget moistened with the otic solution into meatus. Repeat every 1 to 2 h until pain and congestion is relieved.

Otic Instill solution 3 times/day for 2 or 3 days.

General Advice

• Avoid contaminating the dropper with material from the ear, fingers, and other sources.
• Warm the bottle to body temperature.
• A cotton pledget moistened with the product should be inserted into the meatus after removal of earwax.

Storage/Stability

Store between 68° and 77°F. Protect from light, heat, and freezing.

Drug Interactions

None well documented.

Precautions

Pregnancy

Category C .

Lactation

Undetermined.

Patient Information

• Remind patient, family, or caregiver that medication is for use in the ear only.
• Teach patient proper technique for instilling ear drops: wash hands; do not allow dropper to touch ear. Tilt head to side or lie on side; instill prescribed number of drops; moisten cotton pledget and insert into ear canal; replace dropper.
• Advise patient, family, or caregiver to only use supplied dropper and to not rinse dropper after use.
• Advise patient, family, or caregiver to notify health care provider if symptoms do not improve or if irritation, inflammation, or itching of ear canal is noted.

Copyright © 2009 Wolters Kluwer Health.