Montelukast sodium
Generic name: Montelukast sodium
Brand names: Singulair
Why is Montelukast sodium prescribed?
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Singulair is used for long-term prevention of asthma. It reduces the swelling and inflammation that tend to close up the airways, and relaxes the walls of the bronchial tubes, expanding the airways and permitting more air to pass through.
Singulair is also used to relieve the stuffy, runny nose and sneezing caused by seasonal allergies.
Most important fact about Montelukast sodium
Singulair alleviates the on-going symptoms of asthma, but it won't stop an acute asthma attack. For that you need a fast-acting, orally inhaled airway opener such as Alupent or Proventil.
How should you take Montelukast sodium?
Take a Singulair tablet once daily, whether or not you have any symptoms. The tablet can be taken with or without food.
If you have asthma, or asthma plus allergies, take Singulair in the evening. If you have only allergies, you can take Singulair at any time.
The oral granules should be given directly in the child's mouth. The granules can also be mixed with a spoonful of one of the following soft foods: applesauce, carrots, rice, or ice cream. The food should be cold or at room temperature.
The granules should not be dissolved in liquids before giving them to your child. However, the child can drink liquids after the granules have been swallowed. Do not open the granules packet until your child is ready to take them. Once the packet is opened, the full dose of medication must be given within 15 minutes. Throw away any unused portion of the granules; do not store them for future use.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
--Storage instructions...
Store at room temperature, away from moisture and light.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Singulair.
- More common side effects may include:
Abdominal pain, abnormal dreams, allergic reaction, bronchitis, bruising, cough, dental pain, diarrhea, difficulty breathing or swallowing, dizziness, drowsiness, ear infection, ear pain, eczema, eye inflammation, fatigue, fever, flu, hallucinations, headache, hives, indigestion and other digestive problems, infection, insomnia, irritability, itching, laryngitis, leg pain, muscle aches and cramps, nasal congestion, nausea, pancreatitis, pneumonia, rash, restlessness, runny nose, seizures, sinus pain, skin inflammation, sneezing, sore throat, swelling due to fluid retention, swelling of the mouth or throat, upper respiratory infection, tendency to bleed easily, thirst, viral infection, vomiting
Why should Montelukast sodium not be prescribed?
If Singulair gives you an allergic reaction, you cannot continue using the drug.
Special warnings about Montelukast sodium
After you begin taking Singulair, your doctor may be able to slowly reduce the dosage of other asthma medications such as inhaled steroids. However, Singulair is not a complete replacement for such drugs, so you should not abruptly stop using them unless your doctor recommends it. If your asthma symptoms get worse or you develop a rash, numbness, or heart problems as you reduce your dose of steroids, check with your doctor. Such reactions usually result from a reduction in oral steroid therapy.
If your asthma gets worse after exercise, you'll need to continue using a short-acting inhaled airway opener to prevent the problem and relieve attacks.
If you are allergic to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), you should continue to avoid them. Singulair does not remedy this problem.
If you have difficulty breathing while taking Singulair, or find that you need your orally inhaled bronchodilator more often than usual (or require more puffs than prescribed), notify your doctor.
If you have a child with phenylketonuria--an inability to process phenylalanine that quickly leads to mental retardation--you should be aware that Singulair chewable tablets contains this substance.
Possible food and drug interactions when taking Montelukast sodium
If Singulair is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Singulair with the following:
Phenobarbital
Rifampin (Rifadin, Rifamate, Rimactane)
Special information if you are pregnant or breastfeeding
Singulair should be used during pregnancy only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately.
It is not known whether Singulair appears in breast milk. Because many drugs do make their way into breast milk, use Singulair with caution if you are breastfeeding.
Recommended dosage
ADULTS AND CHILDREN 15 AND OVER
Asthma
The usual dose is one 10-milligram tablet once a day in the evening.
Allergies
The usual dose is one 10-milligram tablet once a day taken at any time.
CHILREN 6 TO 14 YEARS OLD
Asthma
The usual dose is one 5-milligram chewable tablet once a day in the evening.
Allergies
The usual dose is one 5-milligram chewable tablet once a day taken at any time.
CHILDREN 2 TO 5 YEARS OLD
Asthma
The dosage is one 4-milligram chewable tablet or one packet of 4-milligram oral granules per day, taken in the evening.
Allergies
The dosage is one 4-milligram chewable tablet or one packet of 4-milligram oral granules per day, taken at any time.
CHILDREN 12 TO 23 MONTHS OLD
Asthma
The dosage is one packet of 4-milligram oral granules taken once a day in the evening.
The safety and effectiveness of Singulair for treating asthma in children under 12 months have not been studied.
Allergies
Singulair is not approved for treating allergies in children under 2 years old.
Overdosage
Little is known about the effects of Singulair overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
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Hay Fever, Asthma -- Maintenance, Bronchospasm Prophylaxis
