Methylergonovine maleate
Generic name: Methylergonovine maleate
Brand names: Methergine
Why is Methylergonovine maleate prescribed?
Methergine, a blood-vessel constrictor, is given to prevent or control excessive bleeding following childbirth. It works by causing the uterine muscles to contract, thereby reducing the mother's blood loss.
Methergine comes in tablet and injectable forms.
Most important fact about Methylergonovine maleate
Some blood-vessel disorders and certain infections make the use of Methergine dangerous. Make sure your doctor is aware of any medical conditions you may have.
How should you take Methylergonovine maleate?
Take Methergine tablets exactly as prescribed.
--If you miss a dose...
Do not take the missed dose at all and do not double the next one. Instead, go back to your regular schedule.
--Storage instructions...
Store at room temperature in a tightly closed container, away from light.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Methergine.
The most common side effect is high blood pressure, which may cause a headache or even a seizure. In some people, however, Methergine may cause low blood pressure.
Why should Methylergonovine maleate not be prescribed?
You should not take Methergine if you are allergic to it, if you are pregnant, or if you have high blood pressure or toxemia (poisons circulating in the blood).
Special warnings about Methylergonovine maleate
It may be dangerous to take Methergine if you have an infection, certain blood vessel disorders, or a liver or kidney problem. Inform your doctor if you think you have any such condition.
Your doctor will use intravenous Methergine only when necessary, because of the possibility of a sudden rise in blood pressure or a stroke.
Possible food and drug interactions when taking Methylergonovine maleate
If Methergine is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is especially important to check with your doctor before combining Methergine with the following:
Other blood-vessel constrictors such as EpiPen
Other ergot-derived medications such as Ergotrate
Special information if you are pregnant or breastfeeding
Methergine should not be taken during pregnancy. Methergine appears in breast milk. Although no specific information is available about possible effects of Methergine on a nursing baby, the general rule is that a mother who is breastfeeding should not take any drug unless it is clearly needed.
Recommended dosage
The usual dose is 1 tablet (0.2 milligram) 3 or 4 times daily after childbirth for a maximum of 1 week.
Overdosage
Any medication taken in excess can have serious consequences. If you suspect symptoms of a Methergine overdose, seek medical attention immediately.
- Symptoms of Methergine overdose may include:
Abdominal pain, coma, convulsions, elevated blood pressure, hypothermia (drop in body temperature), lowered blood pressure, nausea, numbness, slowed breathing, tingling of the arms and legs, vomiting
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