Levemir

Generic name: Insulin detemir [rDNA origin]
Brand names: Levemir

Why is Levemir prescribed?

Levemir is used to treat children and adults with type 1 diabetes and adults with type 2 diabetes for the control of high blood sugar. It is taken once or twice a day.

Most important fact about Levemir

Low blood sugar (hypoglycemia) is the most common side effect of Levemir. Blood sugar levels must be always be monitored if you have diabetes. Also, do not use Levemir with an insulin infusion pump.

How should you take Levemir?

Levemir should be injected just under the skin of your upper leg, stomach, or upper arm. Injection sites should be rotated.

• Storage instructions...
  Store in a refrigerator; do not freeze Levemir.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Levemir.

• Side effects may include:
  Allergic reactions/injection site reactions, low blood sugar (hypoglycemia), rash, weight gain

Why should Levemir not be prescribed?

Do not take Levemir if you are allergic to any of its ingredients.

Special warnings about Levemir

Do not inject Levemir in the same place twice; rotate injection sites. Do not mix this insulin with any other insulin, and should only be used if the solution is clear and colorless.

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking to avoid a possible interaction with Levemir. Also talk with your doctor about your complete medical history, especially if you have kidney or liver problems.

Possible food and drug interactions when taking Levemir

If Levemir is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Levemir with the following:

ACE inhibitors
Antidiabetic drugs (oral)
Beta-blockers
Clonidine
Corticosteroids
Danazol
Disopyramide
Diuretics
Estrogens
Fibrates
Fluoxetine
Guanethidine
Isoniazid
MAO inhibitors
Phenothiazine derivatives
Progestogens (such as in oral contraceptives)
Propoxyphene
Reserpine
Salicylates
Somatostatin analog (such as octreotide)
Somatropin
Sulfonamide antibiotics
Sympathomimetic agents (such as epinephrine, albuterol, terbutaline)
Thyroid hormones

Special information if you are pregnant or breastfeeding

Before taking Levemir, talk to your doctor if you are pregnant, planning to become pregnant, or are breastfeeding. There is a risk of Levemir causing harm to your unborn baby, or passing through your breast milk.

Recommended dosage for Levemir

ADULTS

The usual dose of Levemir is taken once or twice a day. If it is prescribed once daily, it should be taken with either your morning or evening meal. If Levemir is prescribed twice daily, then a morning and an evening dose should be taken 12 hours apart; the second dose can be taken with your evening meal or at bedtime.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

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