Generic Name: iron polysaccharide (I ern paw lee SACK ah ride)
Brand Names: Ezfe, Ferrex-150, Ferus Pic-150, Niferex, Niferex Elixir, Nu-Iron 150, Poly Iron, Polysaccharide Iron

What is Niferex?

Niferex is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood.

Niferex is used as a dietary supplement, and to prevent and to treat iron deficiencies and iron deficiency anemia.

Niferex may also be used for purposes other than those listed in this medication guide.

Important information

Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

Niferex may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking Niferex if you take any other prescription or over-the-counter medicines.

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Who should not take Niferex?

Do not take Niferex if you have
  • hemochromatosis,

  • hemosiderosis, or

  • hemolytic anemia.

Niferex may be dangerous if you have any of the conditions listed above.

If you do not have an iron deficiency, talk to your doctor about the use of Niferex. Generally, iron polysaccharide should not be taken chronically by individuals with a normal iron balance.

Talk to your doctor before taking Niferex if you are pregnant. Talk to your doctor before taking iron polysaccharide if you are breast-feeding a baby.

How should I take Niferex?

Take Niferex exactly as directed by your doctor, or as directed on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each tablet with a full glass of water. Shake the suspension well before measuring a dose. To ensure you get the correct dose, use a dose-measuring cup or spoon, not a regular table spoon to measure the dose. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Mix the liquid forms of iron polysaccharide with water, juice, or another beverage as directed and drink the mixture through a straw to prevent staining of the teeth.

Take Niferex on an empty stomach for best results. If stomach upset occurs, take Niferex with food or following a meal.

This medicine may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking Niferex if you take any other prescription or over-the-counter medicines.

Store this medicine at room temperature, away from moisture and heat. Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time to take the next dose, skip the dose you missed and take the next regularly scheduled dose as directed. Do not take a double dose.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a iron polysaccharide overdose include decreased energy; nausea; vomiting; abdominal pain; tarry stools; a weak, rapid pulse; fever; coma; seizures; and death.

What should I avoid?

Keep Niferex out of the reach of children. An accidental overdose of iron by a child can be fatal.

This medicine may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking Niferex if you take any other prescription or over-the-counter medicines.

Niferex side effects

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking Niferex and seek emergency medical attention.

Other less serious side effects are more likely to occur. Continue taking Niferex and talk to your doctor or pharmacist if you experience

  • stomach upset,

  • nausea or vomiting,

  • constipation,

  • diarrhea,

  • black or darker than normal appearing stools, or

  • temporary staining of the teeth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Niferex?

Do not take Niferex within 2 hours of a dose of any of the following medicines
  • a tetracycline antibiotic such as tetracycline (Achromycin, Sumycin), minocycline (Minocin, Dynacin), doxycycline (Vibramycin, Monodox), demeclocycline (Declomycin), oxytetracycline (Terramycin), or troleandomycin (TAO);

  • a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), enoxacin (Penetrex) ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), sparfloxacin (Zagam), or trovafloxacin (Trovan);

  • levodopa (Larodopa, Dopar, Sinemet);

  • levothyroxine (Synthroid, Levoxyl, others);

  • methyldopa (Aldomet); or

  • penicillamine (Cuprimine).

Iron polysaccharide may decrease the absorption of the drugs listed above.

Do not take antacids within 2 hours of a dose of Niferex. Antacids may decrease the absorption of iron polysaccharide.

Drugs other than those listed here may also interact with Niferex. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines while taking iron polysaccharide.

Where can I get more information?

  • Your pharmacist can provide more information about Niferex.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2014 Cerner Multum, Inc. Version: 1.09. Revision Date: 4/12/2009 4:41:50 PM.
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