Warning of increased risk of lymphoma for patients taking Remicade
Warning of increased risk of lymphoma for patients taking Remicade
October 8, 2004 -- Centocor Inc. sent a letter to health care professionals warning that patients taking Remicade (infliximab) for rheumatoid arthritis were approximately three times as likely to develop lymphoma than the general public, according to the Associated Press.
Data from completed clinical trials for all patients taking the drug revealed a six-fold increased risk of developing lymphoma.
The company has updated its label for Remicade, which is indicated to treat rheumatoid arthritis and Crohn's disease, to reflect this lymphoma risk. Centocor noted the label change is in line with warnings recently added to other drugs in its class that act by blocking overproduction of tumor necrosis factor, according to the AP.
Centocor also revised the Remicade label in August. At that time, the company said some patients receiving Remicade have reported cases of leukopenia, neutropenia, thrombocytopenia and pancytopenia.
Last week, the Food and Drug Administration approved a Remicade (infliximab) regimen -- a combination of Remicade and methotrexate -- as a first-line treatment for patients with rheumatoid arthritis. The expanded label eliminates the requirement that patients must fail on methotrexate treatment before they can start receiving the Remicade regimen.
Source: News reports
Norditropin is indicated for the long-term treatment of children who have growth failure due to inadequate secretion of endogenous growth hormone. Norditropin should not be used in children who are allergic to phenol or any other ingredients in the medicine. Side effects may include headache, muscle pain, weakness, mild hyperglycemia, glucosuria, peripheral edema and fluid retention, and localized reactions at the injection site.
Source: Novo Nordisk www.novonordisk.com
Pharma Industry News Archive
2007: Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec
2006: Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec
2005: Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec
2004: Jan | Feb | Mar | Apr | May | Jul | Aug | Sep | Oct | Nov | Dec
2003: Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec
2002: Jan | Apr | May | Jun | Aug | Sep | Oct | Nov | Dec






