Acomplia (rimonabant) is Reimbursed in Switzerland for the Treatment of Type 2 Diabetics Overweight Patients and for the Treatment of Patients with ObesityPARIS, April 24, 2007 - Sanofi-aventis announced today that the Swiss Federal Register of Public Health has registered ACOMPLIA® (rimonabant) as of May 1, 2007 on the reimbursement list.
ACOMPLIA® is reimbursed by the mandatory social security system for the treatment of type 2 diabetic overweight patients (Body Mass Index - BMI - greater than or equal 28 kg/m2) on at least one oral antidiabetic. ACOMPLIA® is furthermore reimbursed for the treatment of patients with obesity (BMI greater than or equal 35 kg/m2).
ACOMPLIA® will be available at a price similar to those obtained in the countries of the European Union.
In Switzerland, ACOMPLIA® is indicated in association with a light hypocaloric diet and physical activity for obese patients (Body Mass Index - BMI - greater than or equal to 30 kg/m2) or for overweight patients (BMI greater than or equal to 27 kg/m2) with at least one associated cardiovascular risk factor, when measures taken to reduce weight, such as diet and/or physical activity turned out to be insufficient.
ACOMPLIA® is the first member of a new therapeutic class: the CB1 receptor antagonists. The marketing authorisation is based on a thorough analysis of the safety and efficacy results and the assessment of the pivotal clinical trial program of the phase III. These results have shown that ACOMPLIA® at 20 mg per day (1 tablet) significantly reduces weight, waist circumference, HBA1c, triglycerides, at the same time improving significantly the patients’ HDL ("good cholesterol").
Sanofi-aventis is one of the world leaders in the pharmaceutical industry, ranking number one in Europe. Backed by a world-class R&D organisation, sanofi-aventis is developing leading positions in seven major therapeutic areas: cardiovascular, thrombosis, oncology, metabolic
diseases, central nervous system, internal medicine and vaccines. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).
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Posted: April 2007