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August 2007

August 1

Amgen Responds to Final CMS National Coverage Determination on Use of Erythropoiesis-Stimulating Agents in Oncology Sanofi-aventis First Half 2007: Solid Results in a Difficult Context; SurModics Acquires Brookwood Pharmaceuticals Advanced Cell Technology Enters Into Definitive Merger Agreement With Mytogen, Inc. Teva Reports Second Quarter 2007 Results Southern Research Institute Spinout, Brookwood Pharmaceuticals, Acquired by SurModics for $62 Million Cell Therapeutics, Inc. Completes Acquisition of SMi Allergan Reports Second Quarter Operating Results Court Takes Matter of Wyeth's Motion for Preliminary Injunction Under Advisement; Obtains Agreement from Teva and Sun to Delay Any Potential Launch of Generic Pantoprazole Beijing Med-Pharm Announces That Alliance BMP Limited Has Received MOFCOM Approval to Acquire Interest in Guangzhou Pharmaceutical Corporation Reorganisation of Astellas European Business Functions Publicis Groupe Launches SSF Group

August 3

BIO Applauds Court of Appeals Decision FDA, Defense Department Share Data to Enhance Medical Product Safety Reviews Regeneron and Bayer HealthCare Initiate Phase 3 Global Development Program For VEGF Trap-Eye In Wet Age-Related Macular Degeneration (AMD) Novo Nordisk: Financial Statement for the Period 1 January 2007 to 30 June 2007 A Voluntary Recall of a Specific Batch of “Vesanoid Capsule,” a Treatment for Acute Promyelocytic Leukemia Appeals Court Strikes Down D.C. Drug Price Control Law Novo Nordisk Increased First Half-Year Operating Profit by 14% and Raises the Expectation for 2007 Operating Profit Growth to Around 10% GlaxoSmithKline Receives New HHS Order for H5N1 Bulk Antigen. First North American Clinical Trials with GSK's Candidate Pre-pandemic Flu Vaccine to Start. Healthcare Acquisition Corp. and PharmAthene Receive Stockholder Approval for Their Merger

August 7

King Pharmaceuticals Reports Second-Quarter 2007 Financial Results KineMed and Merck Enter Collaboration in Atherosclerosis Pfizer Says Growth in Phase II Portfolio Supports Goal of Tripling Phase III Portfolio by 2009 Healthcare Acquisition Corp. and PharmAthene, Inc. File Certificate of Merger to Complete Acquisition; Confirmation to Be Sought from Delaware Court of Chancery Regarding Stockholder Vote Bayer Continues On a Path of Growth ADHD Appears to Be Associated with Depressed Dopamine Activity in the Brain Marketing Authorisation for the Antiretroviral Medicinal Product Viracept is Suspended Multicultural Marketing of Health and Wellness to Women. the Trend Report Examines Ethnic & Demographic Differences in Health-care-related Opinions and Behaviors Asia Pacific to Replace United States and Europe as Pharmaceutical Industry Powerhouse, Finds PricewaterhouseCoopers Court Denies Terminally Ill Access to Experimental Drugs

August 16

Amgen Restructures Due to Lower Aranesp Revenues While Continuing to Invest in Innovation and Future Growth Baxter Awarded Pandemic Advanced Supply Contract from the Department of Health Cell Therapeutics, Inc. (CTI) Enters Agreement to Acquire Lymphoma Drug Zevalin from Biogen Idec for Sales and Marketing in the United States EvoGenix to Commence Second Project with GlaxoSmithKline GlaxoSmithKline Signs Contract for Its Pandemic Flu Vaccine with UK Government Parion Sciences and Gilead Sciences Sign Agreement to Advance Drug Candidates for Pulmonary Disease Novartis Starts US Shipment of Fluvirin Allowing for Early Influenza Vaccination of Millions of Americans Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for Xiaflex NEJM Direct-to-Consumer Ad Study Shows Drug Industry Incapable of Self- Regulation, Says AHF New Clinical Trial Guidelines Reflect Northwick Park Lessons Shanghai Century Acquisition Corporation Files Preliminary Proxy Statement FDA Approves Updated Warfarin (Coumadin) Prescribing Information FDA Announces Baraclude (entecavir) is Not Recommended for HIV/HBV Co-infected patients who are not also receiving HAART due to the potential for the development of HIV resistance Spherix Shareholders Support Company's Focus on Naturlose, Biotechnology

August 20

Alcon's Tender Offer Endorsed by WaveLight AG's Executive Committee and Supervisory Board Pharming Reports Positive Results in European Placebo-Controlled Trial of Rhucin in Hereditary Angioedema PDL BioPharma Announces Internal CEO Investigation Found No Credible Evidence of Improper Personal Conduct or Breach of Fiduciary Duty MarkMonitor Brandjacking Index Exposes Online Scams That Threaten Top Pharmaceutical Brands and Hurt Consumers The Medical House PLC: Disposal of Needle-Free Insulin Injector Business (the “Disposal”) Chi-Med Announces Drug Discovery and Development Agreement with Eli Lilly and Company Mackler, Fisher, and Alta Communications Acquire HMP Communications FDA Approves ImClone Systems' New State-of-the-Art Manufacturing Facility PCMA: Minnesota is First in the Nation to Require E-Prescribing

August 28

KineMed to Collaborate With Merck KgaA to Validate New Applications for Drug Development Candidates Human Genome Sciences Announces $40 Million Milestone Payment Related to Albuferon Development Curis Updates Research on Hedgehog Agonist Protein Program for Cardiovascular Disease Indications Multicultural Marketing of Health and Wellness to Women. the Trend Report Examines Ethnic & Demographic Differences in Health-care-related Opinions and Behaviors Xoma Licenses Antibody Technology to Pfizer Practicing What They Preach: GSK Announces Employee Wellness Initiative Statin Treatment May Curb Alzheimer's Brain Changes Sunesis Pharmaceuticals Announces Reorganization to Focus Resources and Build Value in Clinical-Stage Programs Inflazyme Pharmaceuticals Does Not Exercise Option with Helicon Therapeutics to PDE4 Inhibitor, IPL455,903, in Learning and Memory Disorders

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