Generic Name: diazepam (dye AZ e pam)
Brand Name: Valium
What is Valrelease (diazepam)?
Diazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peens). Diazepam affects chemicals in the brain that may become unbalanced and cause anxiety.
Diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Diazepam is sometimes used with other medications to treat seizures.
Diazepam may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Valrelease (diazepam)?
You should not use this medication if you are allergic to diazepam or similar medicines (Ativan, Klonopin, Restoril, Xanax, and others), or if you have myasthenia gravis, severe liver disease, narrow-angle glaucoma, a severe breathing problem, or sleep apnea.
Do not give this medication to a child younger than 6 months old.
What should I discuss with my healthcare provider before taking Valrelease (diazepam)?
You should not use this medication if you are allergic to diazepam or similar drugs (Ativan, Klonopin, Restoril, Xanax, and others), or if you have:
myasthenia gravis (a muscle weakness disorder);
severe liver disease;
a severe breathing problem; or
sleep apnea (breathing stops during sleep).
To make sure diazepam is safe for you, tell your doctor if you have any of these conditions:
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
kidney or liver disease;
epilepsy or other seizure disorder;
a history of mental illness, depression, or suicidal thoughts or behavior; or
a history of drug or alcohol addiction.
Diazepam may be habit forming. Never share diazepam with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category D. If you take diazepam for anxiety, alcohol withdrawal, or muscle spasms, do not use this medicine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. Diazepam may cause low blood pressure, breathing problems, or addiction and withdrawal symptoms in a newborn if the mother takes the medication during pregnancy.
If you take diazepam for seizures, do not start or stop taking diazepam during pregnancy without your doctor's advice. Diazepam may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking diazepam for seizures.
Diazepam can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Do not give this medication to a child younger than 6 months old.
The sedative effects of diazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking diazepam.
How should I take Valrelease (diazepam)?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Diazepam should be used for only a short time. Do not take this medication for longer than 12 weeks (3 months) without your doctor's advice.
Do not stop using diazepam suddenly, or you could have increased seizures or unpleasant withdrawal symptoms. Ask your doctor how to safely stop using diazepam.
Call your doctor at once if you feel that this medicine is not working as well as usual, or if you think you need to use more than usual.
While using diazepam, you may need frequent blood tests at your doctor's office.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Diazepam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
See also: Valrelease dosage (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diazepam can be fatal.
Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, or fainting.
What should I avoid while taking Valrelease (diazepam)?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not drink alcohol while taking diazepam. This medication can increase the effects of alcohol.
Grapefruit and grapefruit juice may interact with diazepam and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
Valrelease (diazepam) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
confusion, hallucinations, unusual thoughts or behavior;
unusual risk-taking behavior, decreased inhibitions, no fear of danger;
depressed mood, thoughts of suicide or hurting yourself;
hyperactivity, agitation, aggression, hostility;
new or worsening seizures;
weak or shallow breathing, a feeling like you might pass out;
muscle twitching, tremor;
loss of bladder control; or
little or no urinating.
Common side effects may include:
drowsiness, tired feeling, memory problems;
dizziness, spinning sensation;
feeling restless or irritable;
drooling or dry mouth, slurred speech;
blurred vision, double vision;
mild skin rash, itching; or
loss of interest in sex.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Valrelease side effects (in more detail)
What other drugs will affect Valrelease (diazepam)?
Taking diazepam with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking diazepam with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with diazepam, especially:
an antibiotic--clarithromycin, erythromycin, telithromycin;
an antidepressant such as fluoxetine, fluoxetine, and others;
antifungal medicine--itraconazole, ketoconazole, voriconazole;
heart or blood pressure medication such as diltiazem, nicardipine, quinidine, verapamil, and others; or
HIV/AIDS medicine--atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, saquinavir, or ritonavir.
This list is not complete. Other drugs may interact with diazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More Valrelease resources
- Diazepam Monograph (AHFS DI)
- diazepam MedFacts Consumer Leaflet (Wolters Kluwer)
- Diazepam Professional Patient Advice (Wolters Kluwer)
- diazepam Advanced Consumer (Micromedex) - Includes Dosage Information
- Diastat Prescribing Information (FDA)
- Diastat Advanced Consumer (Micromedex) - Includes Dosage Information
- Diastat gel MedFacts Consumer Leaflet (Wolters Kluwer)
- Diastat AcuDial gel MedFacts Consumer Leaflet (Wolters Kluwer)
- Valium Prescribing Information (FDA)
- Valium MedFacts Consumer Leaflet (Wolters Kluwer)
- Valium Consumer Overview
Compare Valrelease with other medications
Where can I get more information?
- Your pharmacist can provide more information about diazepam.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 12.02. Revision Date: 2013-04-03, 10:02:16 AM.