Tisseel

Generic Name: fibrin sealant topical (FYE brin SEE lant TOP i kal)
Brand Name: Artiss, Artiss Duo Set, Artiss Duploject, Tisseel, Tisseel Duploject Kit, Tisseel Valupak Kit

What is Tisseel (fibrin sealant topical)?

Fibrinolysis inhibitor and thrombin are agents that are involved in blood clotting.

Fibrin sealant topical is used to cause blood clotting during surgery or due to trauma when natural blood clotting processes are deficient.

Fibrin sealant topical may also be used for purposes other than those listed here.

What is the most important information I should know about Tisseel (fibrin sealant topical)?

Fibrin sealant topical is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although fibrin sealant topical is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with your doctor the risks and benefits of using fibrin sealant topical.

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Contact your doctor if you develop fever, drowsiness, chills, runny nose, rash, joint pain, poor appetite, tiredness, nausea, vomiting, abdominal pain, dark-colored urine, or yellowing of the skin or eyes following treatment with fibrin sealant topical. These may be symptoms of infections that may occur due to use of this product.

What should I discuss with my healthcare provider before using Tisseel (fibrin sealant topical)?

Do not use fibrin sealant topical without first talking to your doctor if you are allergic to cows or products derived from cows.

Fibrin sealant topical is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use fibrin sealant topical without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether fibrin sealant topical will be harmful to a nursing baby. Do not use fibrin sealant topical without first talking to your doctor if you are breast-feeding a baby.

How should I use Tisseel (fibrin sealant topical)?

Fibrin sealant topical will be administered by a healthcare professional as a topical application.

What happens if I miss a dose?

Due to the indications for use and the method of application of fibrin sealant topical, missing a dose is not likely to occur.

What happens if I overdose?

Due to the indications for use and the method of application of fibrin sealant topical, an overdose of the medication is unlikely to occur. Contact your doctor or a poison control center for advice if an overdose is suspected.

What should I avoid while taking Tisseel (fibrin sealant topical)?

There are no restrictions on food, beverages, or activity following the use of fibrin sealant topical, unless otherwise directed by your doctor.

Tisseel (fibrin sealant topical) side effects

Fibrin sealant topical is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although fibrin sealant topical is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with your doctor the risks and benefits of using fibrin sealant topical.

Contact your doctor if you develop fever, drowsiness, chills, runny nose, rash, joint pain, poor appetite, tiredness, nausea, vomiting, abdominal pain, dark-colored urine, or yellowing of the skin or eyes following treatment with fibrin sealant topical. These may be symptoms of infections that may occur due to use of this product.

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to fibrin sealant topical.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect fibrin sealant topical

It is not known whether other medications will interact with fibrin sealant topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products during treatment with fibrin sealant topical.

Where can I get more information?

  • Your pharmacist has additional information about fibrin sealant topical written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.04. Revision Date: 2010-12-15, 5:01:39 PM.

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