pentazocine

Pronunciation

Generic Name: pentazocine (pen TAZ oh seen)
Brand Name: Talwin Lactate, Talwin

What is pentazocine?

Pentazocine is an opioid pain medication. An opioid is sometimes called a narcotic.

Pentazocine is used to treat moderate to severe pain. It is also used as part of anesthesia for surgery.

Pentazocine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about pentazocine?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

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What should I discuss with my health care provider before using pentazocine?

You should not use pentazocine if you are allergic to it.

To make sure pentazocine is safe for you, tell your doctor if you have:

  • any type of breathing problem or lung disease;

  • asthma or sulfite allergy;

  • a history of head injury, brain tumor, or mental illness;

  • a history of alcoholism or drug addiction (pentazocine may be habit-forming);

  • a seizure disorder;

  • high blood pressure, heart disease, history of recent heart attack;

  • liver or kidney disease; or

  • gallbladder disease.

This medicine is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

FDA pregnancy category C. It is not known whether pentazocine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether pentazocine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Serious side effects may be more likely in older adults and those who are ill or debilitated.

How is pentazocine given?

Pentazocine is injected under the skin or into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.

This medicine is usually given as a single dose.

You may have unpleasant withdrawal symptoms if you stop using pentazocine suddenly after long-term use. If you receive more than a single dose, ask your doctor how to avoid withdrawal symptoms when you stop using pentazocine.

What happens if I miss a dose?

Since pentazocine is used when needed and given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while using pentazocine?

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with pentazocine.

Pentazocine may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Pentazocine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain, burning, irritation, or skin changes where the injection was given;

  • confusion, hallucinations;

  • weak or shallow breathing;

  • painful or difficult urination; or

  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • headache, dizziness, drowsiness;

  • anxiety, feelings of extreme happiness;

  • constipation; or

  • dry mouth, blurred vision, ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Pentazocine dosing information

Usual Adult Dose for Anesthesia:

Initial dose: 30 mg by intramuscular, subcutaneous, or intravenous route. This may be repeated every 3 to 4 hours.

Doses in excess of 30 mg intravenously or 60 mg intramuscularly or subcutaneously are not recommended.

Maximum daily dose: 360 mg

Usual Adult Dose for Pain:

Initial dose: 30 mg by intramuscular, subcutaneous, or intravenous route. This may be repeated every 3 to 4 hours.

Doses in excess of 30 mg intravenously or 60 mg intramuscularly or subcutaneously are not recommended.

Maximum daily dose: 360 mg

Usual Adult Dose for Labor Pain:

Dose: 30 mg intramuscularly once has been the most common dose administered.

An intravenous 20 mg dose has given adequate pain relief to some patients in labor when contractions become regular. This dose may be given two or three times at two or three hour intervals as needed.

Usual Geriatric Dose for Anesthesia:

Elderly patients generally should be started on low doses of pentazocine and observed closely.

Usual Geriatric Dose for Pain:

Elderly patients generally should be started on low doses of pentazocine and observed closely.

Usual Pediatric Dose for Sedation:

>= 1 year old:
Recommended dose: 0.5 mg/kg by intramuscular injection

What other drugs will affect pentazocine?

Using this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with pentazocine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about pentazocine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.02. Revision Date: 2013-11-05, 12:04:31 PM.

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