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Murine Ear Drops

Generic Name: carbamide peroxide (otic) (KAR ba mide per OX ide OH tik)
Brand Name: Auraphene-B, Debrox, Ear Wax, Ear Wax Removal, Mollifene, Murine Ear Drops

What is carbamide peroxide?

Carbamide peroxide otic (for the ears) is used to soften and loosen ear wax, making it easier to remove.

Carbamide peroxide may also be used for purposes not listed in this medication guide.

What is the most important information I should know about carbamide peroxide?

You should not use this medicine if you have a hole in your ear drum (ruptured ear drum), or if you have any signs of ear infection or injury, such as pain, warmth, swelling, drainage, or bleeding.

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What should I discuss with my health care provider before using carbamide peroxide?

You should not use carbamide peroxide otic if you are allergic to it, or if you have a hole in your ear drum (ruptured ear drum).

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

  • recent ear surgery or injury;

  • ear pain, itching, or other irritation;

  • drainage, discharge, or bleeding from the ear; or

  • warmth or swelling around the ear.

It is not known whether carbamide peroxide otic will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

It is not known whether carbamide peroxide otic passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Carbamide peroxide otic should not be used on a child younger than 12 years old.

How should I use carbamide peroxide?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Carbamide peroxide otic comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after using this medicine.

To use the ear drops:

  • Lie down or tilt your head with your ear facing upward. Open the ear canal by gently pulling your ear back, or pulling downward on the earlobe when giving this medicine to a child.

  • Hold the dropper upside down over your ear and drop the correct number of drops into the ear.

  • You may hear a bubbling sound inside your ear. This is caused by the foaming action of carbamide peroxide, which helps break up the wax inside your ear.

  • Stay lying down or with your head tilted for at least 5 minutes. You may use a small piece of cotton to plug the ear and keep the medicine from draining out. Follow your doctor's instructions about the use of cotton.

  • Do not touch the dropper tip or place it directly in your ear. It may become contaminated. Wipe the tip with a clean tissue but do not wash with water or soap.

Carbamide peroxide may be packaged with a bulb syringe that is used to flush out your ear with water. To use the bulb syringe:

  • Fill the syringe with warm water that is body temperature (no warmer than 98 degrees F). Do not use hot or cold water.

  • Hold your head sideways with your ear over a sink or bowl. Gently pull your ear back to open the ear canal. Place the tip of the bulb syringe at the opening of your ear canal. Do not insert the tip into your ear.

  • Squeeze the bulb syringe gently to release the water into your ear. Do not squirt the water with any force, or you could damage your ear drum.

  • Remove the syringe and allow the water to drain from your ear into the sink or bowl.

Do not use carbamide peroxide for longer than 4 days in a row. Call your doctor if you still have excessive earwax after using this medicine, or if your symptoms get worse.

Clean the bulb syringe by filling it with plain water and emptying it several times. Do not use soap or other cleaning chemicals. Allow the syringe to air dry.

Keep the medicine bottle tightly closed and store it in the outer carton at room temperature, away from moisture and heat.

What happens if I miss a dose?

Since carbamide peroxide otic is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of carbamide peroxide otic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using carbamide peroxide?

Avoid getting this medicine in your eyes or mouth.

Do not use other ear drops unless your doctor has told you to.

Carbamide peroxide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using carbamide peroxide otic and call your doctor at once if you have:

  • dizziness; or

  • new or worsening ear problems.

Common side effects may include:

  • a foaming or crackling sound in the ear after using the ear drops;

  • temporary decrease in hearing after using the drops;

  • mild feeling of fullness in the ear; or

  • mild itching inside the ear.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect carbamide peroxide?

It is not likely that other drugs you take orally or inject will have an effect on carbamide peroxide used in the ears. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Where can I get more information?

  • Your pharmacist can provide more information about carbamide peroxide.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01. Revision Date: 2014-09-13, 8:26:16 AM.

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