Lithostat

Generic Name: acetohydroxamic acid (a SEET oh HYE drox AM ik AS id)
Brand Name: Lithostat

What is Lithostat (acetohydroxamic acid)?

Acetohydroxamic acid works by preventing bacteria from increasing ammonia levels in urine. Increased ammonia in urine can lead to a certain type of kidney stone.

Acetohydroxamic acid is used together with antibiotics to treat bladder infections caused by bacteria that can increase ammonia levels in the urine.

Acetohydroxamic acid may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Lithostat (acetohydroxamic acid)?

This medication can cause birth defects. Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before using acetohydroxamic acid, tell your doctor if you have kidney disease, a history of blood clot or stroke, hemolytic anemia (a lack of red blood cells), or a weak immune system.

Take acetohydroxamic acid on an empty stomach, at least 1 hour before or 2 hours after a meal. Acetohydroxamic acid is usually taken 3 or 4 times daily. Follow your doctor's instructions.

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Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Acetohydroxamic acid is not an antibiotic and will not treat a bacterial infection alone. Take your antibiotic medication as directed.

Avoid drinking alcohol. Drinking alcohol while taking this medication can cause you to have warmth, redness, or tingling under your skin. This may be an unpleasant side effect.

Call your doctor at once if you have a serious side effect such as chest pain, fast or pounding heartbeats, pale or yellowed skin, dark colored urine, fever, confusion or weakness, mood changes, confusion, anxiety, tremors or shaking, easy bruising or bleeding, flu symptoms, or pain or swelling in one or both legs.

What should I discuss with my health care provider before taking Lithostat (acetohydroxamic acid)?

Before using acetohydroxamic acid, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;

  • a history of blood clot or stroke;

  • hemolytic anemia (a lack of red blood cells); or

  • a weak immune system.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use acetohydroxamic acid.

FDA pregnancy category X. This medication can cause birth defects. Do not use acetohydroxamic acid if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medication.

Acetohydroxamic acid may pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Lithostat (acetohydroxamic acid)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take acetohydroxamic acid on an empty stomach, at least 1 hour before or 2 hours after a meal.

Acetohydroxamic acid is usually taken 3 or 4 times daily. Follow your doctor's instructions.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Acetohydroxamic acid is not an antibiotic and will not treat a bacterial infection alone. Take your antibiotic medication as directed.

To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.

Store acetohydroxamic acid at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Remember to acetohydroxamic acid on an empty stomach.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include weakness, loss of appetite, nausea, vomiting, or tremors.

What should I avoid while taking Lithostat (acetohydroxamic acid)?

Avoid drinking alcohol. Drinking alcohol while taking this medication can cause you to have warmth, redness, or tingling under your skin. This may be an unpleasant side effect.

Avoid taking vitamin or mineral supplements that contain iron, unless your doctor has told you to.

Lithostat (acetohydroxamic acid) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • chest pain, fast or pounding heartbeats;

  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;

  • mood changes, confusion, anxiety;

  • tremors or shaking;

  • easy bruising or bleeding;

  • sore throat, body aches, flu symptoms; or

  • pain or swelling in one or both legs.

Less serious side effects may include:

  • mild nausea, vomiting, upset stomach;

  • loss of appetite;

  • headache; or

  • hair loss.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Lithostat (acetohydroxamic acid)?

There may be other drugs that can interact with acetohydroxamic acid. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about acetohydroxamic acid.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 1.03. Revision Date: 2010-12-15, 5:01:39 PM.

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