Empirin with Codeine

Generic Name: aspirin and codeine (AS pir in and KOE deen)
Brand Name:

What is Empirin with Codeine (aspirin and codeine)?

Aspirin is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation.

Codeine is an opioid pain medication. An opioid is sometimes called a narcotic.

Aspirin and codeine is a combination medicine used to treat moderate to severe pain.

Aspirin and codeine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Empirin with Codeine (aspirin and codeine)?

Codeine can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Codeine may also be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Medicines that contain codeine should not be given to a child just after surgery to remove the tonsils or adenoids.

Get emergency medical help if a child taking this medicine has breathing problems, blue lips, or severe drowsiness, or if you cannot wake the child up from sleep.

Aspirin may cause stomach or intestinal bleeding, which can be fatal.

What should I tell my healthcare provider before taking Empirin with Codeine (aspirin and codeine)?

Aspirin may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking aspirin.

Medicines that contain codeine should not be given to a child just after surgery to remove the tonsils or adenoids.

You should not take this medicine if you are allergic to aspirin or codeine, or if you have:

  • a bleeding or blood clotting disorder such as hemophilia;

  • ulcer or obstruction in the stomach;

  • severe asthma or breathing problems;

  • an allergy to an NSAID (nonsteroidal-steroidal anti-inflammatory drug) such as Advil, Aleve, Motrin, Naprosyn, Orudis, Cataflam, Celecoxib, Feldene, Indocin, Lodine, Mobic, Relafen, Toradol, Voltaren, and others; or

  • if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).

Do not use aspirin and codeine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

In some people, codeine breaks down rapidly in the liver and reaches higher than normal levels in the body. This can cause dangerously slow breathing and may cause death, especially in a child.

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.

To make sure aspirin and codeine is safe for you, tell your doctor if you have:

  • stomach or intestinal disorder, history of stomach ulcer or bleeding;

  • a blockage in your stomach or intestines;

  • any type of breathing problem or lung disease;

  • allergies, nasal polyps;

  • urination problems;

  • liver or kidney disease;

  • a history of head injury, brain tumor, or seizures;

  • a history of drug abuse, alcohol addiction, or mental illness; or

  • problems with your gallbladder, pancreas, or thyroid.

This medicine is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

FDA pregnancy category C. This medicine can cause breathing problems or addiction/withdrawal symptoms in a newborn. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Do not take aspirin and codeine during pregnancy unless your doctor has told you to. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Aspirin and codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. You should not breast-feed while you are using aspirin and codeine.

How should I take Empirin with Codeine (aspirin and codeine)?

Follow all directions on your prescription label. Codeine can slow or stop your breathing. Never use aspirin and codeine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Codeine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away aspirin and codeine is against the law.

Aspirin and codeine may be taken with food if it upsets your stomach.

If you need surgery, tell the surgeon ahead of time that you are using aspirin and codeine. You may need to stop using the medicine for a short time.

Do not stop using aspirin and codeine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using aspirin and codeine.

Store at room temperature away from moisture, heat, and light. Keep track of the amount of medicine used from each new bottle. Codeine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since aspirin and codeine is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A aspirin and codeine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.

What should I avoid while taking Empirin with Codeine (aspirin and codeine)?

Avoid drinking alcohol. It may increase your risk of stomach bleeding while taking aspirin.

This medicine may impair your thinking or reactions. Avoid driving or operating machinery until you know how aspirin and codeine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Ask a doctor or pharmacist before using any other over-the-counter cold, allergy, or pain medicine. Aspirin is contained in many combination medicines. Taking certain products together can cause you to get too much aspirin. Check the label to see if a medicine contains aspirin.

Ask your doctor before using aspirin and codeine if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.

Empirin with Codeine (aspirin and codeine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; runny nose, wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek emergency medical attention if a child taking this medicine has any of the following life-threatening side effects: noisy breathing, sighing, slow breathing with long pauses between breaths; being unusually sleepy or hard to wake up; blue colored lips.

Call your doctor at once if you have:

  • severe stomach pain or constipation, vomiting;

  • easy bruising, unusual bleeding, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • weak or shallow breathing, fast or slow heartbeat;

  • confusion, hallucinations, unusual thoughts or behavior, feeling like you might pass out;

  • seizure (convulsions); or

  • decreased hearing or ringing in the ears.

Common side effects may include:

  • mild constipation, nausea;

  • heartburn, upset stomach, bloating, gas, diarrhea;

  • headache, dizziness, tired feeling; or

  • mild itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Empirin with Codeine (aspirin and codeine)?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking aspirin and codeine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with aspirin and codeine, especially:

  • medication to prevent blood clots--dalteparin, desirudin, enoxaparin, fondaparinux, tinzaparin, warfarin, Coumadin; or

  • an NSAID (nonsteroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin), ketorolac.

This list is not complete. Other drugs may interact with aspirin and codeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about Empirin with Codeine (aspirin / codeine)

Other formulations

Related treatment guides

Where can I get more information?

  • Your pharmacist can provide more information about aspirin and codeine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 7.04. Revision Date: 2014-01-29, 11:21:06 AM.

Hide
(web2)