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dobutamine

Pronunciation

Generic Name: dobutamine (doe BUE ta meen)
Brand Name: Dobutrex

What is dobutamine?

Dobutamine stimulates heart muscle and improves blood flow by helping the heart pump better.

Dobutamine is used short-term to treat cardiac decompensation due to weakened heart muscle.

Dobutamine is usually given after other heart medicines have been tried without success.

Dobutamine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about dobutamine?

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving dobutamine.

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What should I discuss with my healthcare provider before using dobutamine?

You should not use dobutamine if you are allergic to it.

To make sure dobutamine is safe for you, tell your doctor if you have:

  • high blood pressure;

  • a heart valve disorder; or

  • asthma or sulfite allergy.

FDA pregnancy category B. Dobutamine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether dobutamine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is dobutamine given?

Dobutamine is injected into a vein through a catheter. A healthcare provider will give you this injection.

You will receive this medicine in a hospital or clinic setting to quickly treat any serious side effects that occur.

While using dobutamine, you may need frequent medical tests. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

What happens if I miss a dose?

If you are using the medicine at home, call your doctor for instructions if you miss a dose of dobutamine.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using dobutamine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dobutamine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregiver right away if you have:

  • shortness of breath (even with mild exertion), swelling, rapid weight gain;

  • chest pain, fast or pounding heartbeats;

  • a light-headed feeling, like you might pass out;

  • wheezing, chest tightness;

  • dangerously high blood pressure-severe headache, blurred vision, buzzing in your ears, anxiety, confusion, uneven heartbeats, seizure; or

  • signs of infection in your catheter--pain, swelling, warmth, redness, oozing, or skin changes where the medicine is injected.

Common side effects may include:

  • nausea, vomiting;

  • fever, tingly feeling;

  • headache; or

  • leg cramps.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Dobutamine dosing information

Usual Adult Dose for Congestive Heart Failure:

The rate of infusion needed to increase cardiac output usually ranges from 2.5 to 15 mcg/kg/min. The initial dosage may be titrated upward by 2.5 mcg per kg per minute as tolerated to maintain systemic blood pressure and urine output. Administration rates greater than 40 mcg per kg per min may be necessary in serious situations.

Usual Adult Dose for Shock:

The rate of infusion needed to increase cardiac output usually ranges from 2.5 to 15 mcg/kg/min. The initial dosage may be titrated upward by 2.5 mcg per kg per minute as tolerated to maintain systemic blood pressure and urine output. Administration rates greater than 40 mcg per kg per min may be necessary in serious situations.

What other drugs will affect dobutamine?

Other drugs may interact with dobutamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about dobutamine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.04. Revision Date: 2014-03-28, 11:24:39 AM.

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