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Centrum Singles-Vitamin E

Generic Name: vitamin E (VYE ta min E)
Brand Name: Amino-Opti-E, Aqua-E, Aquasol E, Aquavite-E, Aqueous Vitamin E, E Pherol, E-400 Clear, Vita-Plus E Natural

What is Centrum Singles-Vitamin E (vitamin E)?

Vitamin E is an antioxidant that occurs naturally in foods such as nuts, seeds, and leafy green vegetables. Vitamin E is important for many processes in the body.

Vitamin E is used to prevent and to treat a deficiency vitamin E. People with certain diseases may need extra vitamin E.

Vitamin E may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Centrum Singles-Vitamin E (vitamin E)?

Before using vitamin E, tell your healthcare provider if you have liver disease, diabetes, active bleeding, a vitamin K deficiency, retinitis pigmentosa, chronic diarrhea, if you are being treated for cancer, or if you have a history of heart attack, stroke, blood clot, or recent surgery.

Do not use this product without a doctor's advice your doctor if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing a baby.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Do not take vitamin E without a doctor's advice if you are using any type of medication to treat or prevent blood clots.

There are many other drugs that can interact with or be made less effective by vitamin E. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Stop taking vitamin E and call your doctor at once if you have any unusual bleeding or bruising, or if you feel like you might pass out.

What should I discuss with my healthcare provider before taking Centrum Singles-Vitamin E (vitamin E)?

Before using vitamin E, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to take vitamin E if you have certain medical conditions.

You may need a dose adjustment or special tests if you have:

  • liver disease;

  • diabetes;

  • active or uncontrolled bleeding;

  • a vitamin K deficiency;

  • retinitis pigmentosa;

  • short bowel syndrome;

  • chronic diarrhea;

  • a history of heart attack, stroke, or blood clot;

  • if you have recently had surgery; or

  • if you are receiving cancer treatment (chemotherapy or radiation).

It is not known whether vitamin E is harmful to an unborn baby. Your dose needs may be different during pregnancy. Do not use this product without a doctor's advice if you are pregnant or plan to become pregnant while using vitamin E.

It is not known whether vitamin E passes into breast milk or if it could harm a nursing baby. Your dose needs may be different while you are nursing. Do not use this product without a doctor's advice if you are breast-feeding a baby.

How should I take Centrum Singles-Vitamin E (vitamin E)?

Take exactly as directed on the label, or as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended.

Take vitamin E with a full glass of water.

The chewable tablet must be chewed completely before you swallow it.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

You may take vitamin E with or without food. You do not need to eat extra fat to help your body absorb vitamin E.

The recommended dietary allowance of vitamin E increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include unusual bleeding or bruising.

What should I avoid while taking Centrum Singles-Vitamin E (vitamin E)?

Avoid taking other vitamins, mineral supplements, or nutritional products without your doctor's advice.

Centrum Singles-Vitamin E (vitamin E) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking vitamin E and call your doctor at once if you have a serious side effect such as:

  • feeling like you might pass out;

  • easy bruising; or

  • unusual bleeding (nose, mouth, vagina, or rectum).

Less serious side effects may include:

  • nausea, diarrhea, stomach cramps;

  • tired feeling;

  • headache;

  • blurred vision; or

  • mild rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Centrum Singles-Vitamin E (vitamin E)?

Do not take vitamin E without a doctor's advice if you are using any type of medication to treat or prevent blood clots, such as:

  • heparin, warfarin (Coumadin);

  • alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase);

  • argatroban (Acova), bivalirudin (Angiomax), lepirudin (Refludan);

  • dalteparin (Fragmin), enoxaparin (Lovenox), fondaparinux (Arixtra); or

  • abciximab (ReoPro), anagrelide (Agrylin), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), eptifibatide (Integrelin), prasugrel (Effient), ticlopidine (Ticlid), tirofiban (Aggrastat).

The following drugs can interact with or be made less effective by vitamin E. Tell your doctor if you are using any of these:

  • cyclosporine (Gengraf, Neoral, Sandimmune);

  • diazepam (Valium) and other sedatives;

  • fluoxetine (Prozac) and other antidepressants;

  • mineral oil, orlistat (alli, Xenical);

  • an antibiotic such as clarithromycin (Biaxin), doxycycline (Doryx, Vibramycin), trimethoprim (Bactrim, Septra, SMX-TMP), and others;

  • antifungal medication such as itraconazole (Sporanox) or ketoconazole (Extina, Ketozole, Nizoral, Xolegal);

  • cholesterol-lowering medicines such as atorvastatin (Lipitor), cholestyramine (Questran), colestipol (Colestid), simvastatin (Zocor, Simcor), lovastatin (Mevacor, Advicor), pravastatin (Pravachol), niacin (Niaspan, Slo-Niacin), and others;

  • heart or blood pressure medications such as diltiazem (Cartia, Cardizem), losartan (Cozaar), propranolol (Inderal), verapamil (Calan, Covera, Isoptin), and others;

  • HIV medicines such as fosamprenavir (Lexiva), ritonavir (Norvir, Kaletra), and others;

  • narcotic medication such as fentanyl (Actiq, Duragesic, Fentora);

  • seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), phenytoin (Dilantin), and others; or

  • stomach acid reducers such as cimetidine (Tagamet), omeprazole (Prilosec), lansoprazole (Prevacid), and others.

This list is not complete and there are many other drugs that can interact with vitamin E. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

  • Your pharmacist can provide more information about vitamin E.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.06. Revision Date: 2010-12-15, 5:01:39 PM.

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