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Ceenu

Generic Name: lomustine (LOE mus teen)
Brand Name: CeeNU

What is Ceenu (lomustine)?

Lomustine is a cancer medication that interferes with the growth of cancer cells and slows their spread in the body.

Lomustine is used to treat brain tumors and Hodgkin's disease.

Lomustine is sometimes given with other cancer medications.

Lomustine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Ceenu (lomustine)?

Lomustine can weaken your immune system. Your blood may need to be tested often.

Lomustine can have long lasting effects on your body. You may also need frequent medical tests for a short time after you stop using this medication.

Slideshow: 2013 Drug News Round-Up: Top 20 Stories

What should I discuss with my healthcare provider before taking Ceenu (lomustine)?

You should not use this medication if you are allergic to it.

To make sure lomustine is safe for you, tell your doctor if you have:

  • bone marrow suppression;

  • liver disease;

  • kidney disease; or

  • a history of lung or breathing problems.

FDA pregnancy category D. Do not use lomustine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether lomustine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Ceenu (lomustine)?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Lomustine is usually taken once every 6 weeks. To get the correct dose, you may need to take 2 or more capsules that are different types and colors. Follow your doctor's dosing instructions very carefully.

Lomustine can cause nausea and vomiting but this should last less than 24 hours after your dose. You may have loss of appetite that lasts for several days. Taking lomustine on an empty stomach may reduce nausea and vomiting. You may also be given anti-nausea medications. Call your doctor if you vomit right after taking a lomustine capsule.

Lomustine can weaken your immune system. Your blood may need to be tested often.

Lomustine can have long lasting effects on your body. You may also need frequent medical tests for a short time after you stop using this medication.

Store at room temperature away from heat and moisture. Keep the bottle tightly closed until you are ready to take the medicine.

Wear disposable rubber gloves when you handle a lomustine capsule. Throw the gloves away after one use.

Do not open the lomustine capsule. Do not use a broken pill. The medicine from a broken pill can be dangerous if it gets on your skin. If this occurs, wash with soap and water. Ask your doctor or pharmacist how to safely handle and dispose of a broken capsule.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of lomustine.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

What should I avoid while taking Ceenu (lomustine)?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using lomustine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

This medicine can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Patients and caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

Ceenu (lomustine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • signs of infection such as fever, chills, sore throat, easy bruising or bleeding;

  • wheezing, rapid breathing, feeling short of breath;

  • chest pain, dry cough, fever, feeling ill;

  • urinating less than usual or not at all;

  • confusion, mood changes, increased thirst;

  • swelling in your ankles or feet;

  • jaundice (yellowing of the skin or eyes); or

  • white patches or sores inside your mouth or on your lips.

Common side effects may include:

  • loss of appetite, nausea, vomiting;

  • temporary hair loss;

  • vision problems; or

  • feeling weak or tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Ceenu (lomustine)?

Other drugs may interact with lomustine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about lomustine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02. Revision Date: 2013-07-08, 3:19:06 PM.

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