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carbinoxamine, methscopolamine, and pseudoephedrine

Generic Name: carbinoxamine, methscopolamine, and pseudoephedrine (car bin OX uh meen, meth sko PAW luh meen, and soo doh ee FED rin)
Brand Name: Pannaz, Pannaz S, Pseudox M, Nacon

What is carbinoxamine, methscopolamine, and pseudoephedrine?

Carbinoxamine and methscopolamine are antihistamines that reduce the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Carbinoxamine, methscopolamine, and pseudoephedrine is used to treat sneezing, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Carbinoxamine, methscopolamine, and pseudoephedrine may also be used for purposes other than those listed here.

What is the most important information I should know about carbinoxamine, methscopolamine, and pseudoephedrine?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use a cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cold medicine before the MAO inhibitor has cleared from your body.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

What should I discuss with my healthcare provider before taking carbinoxamine, methscopolamine, and pseudoephedrine?

Do not give this medication to a child younger than 2 years old, even if the label has dosing instructions for children this young. Death can occur from the use of carbinoxamine in very young children. Talk with your doctor about other FDA-approved products available for young children with cold or allergy symptoms.

Do not use a cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to carbinoxamine, methscopolamine, or pseudoephedrine, or if you have:

  • epilepsy or another seizure disorder;

  • peripheral vascular disease such as Raynaud's syndrome;

  • thyroid problems;

  • asthma, emphysema, or chronic obstructive pulmonary disease (COPD);

  • diabetes;

  • glaucoma;

  • an ulcer or an obstruction in the stomach;

  • an enlarged prostate or urination problems;

  • heart disease or high blood pressure;

  • kidney disease; or

  • liver disease.

If you have any of the conditions listed above, you may not be able to take carbinoxamine, methscopolamine, and pseudoephedrine, or you may require a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Carbinoxamine, methscopolamine, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take carbinoxamine, methscopolamine, and pseudoephedrine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Carbinoxamine, methscopolamine, and pseudoephedrine can be taken with or without food.

Take this medicine with a full glass of water.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Call your doctor if you have a fever, or if your symptoms get worse or do not improve after taking this medicine for 7 days.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include dry mouth, blurred vision, flushing, nausea, vomiting, hyperactivity, hallucinations, fainting, or seizure (convulsions).

What should I avoid while taking carbinoxamine, methscopolamine, and pseudoephedrine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by carbinoxamine, methscopolamine, and pseudoephedrine. Tell your doctor if you need to use any of these other medicines while you are taking this drug.

Carbinoxamine, methscopolamine, and pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • feeling light-headed, fainting;

  • urinating less than usual or not at all;

  • wheezing, tightness in your chest;

  • fast or pounding heartbeat; or

  • pale skin, easy bruising or bleeding.

Continue taking this medication and talk to your doctor if you have any of these less serious side effects:

  • drowsiness, dizziness;

  • lack of coordination;

  • upset stomach;

  • stuffy nose, chest congestion;

  • sleep problems (insomnia);

  • feeling restless or excited (especially in children);

  • dry mouth or nose; or

  • blurred vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

See also: Side effects (in more detail)

Carbinoxamine, methscopolamine, and pseudoephedrine dosing information

Usual Adult Dose for Rhinitis:

Syrup: 5 to 10 mL orally four times a day.

Tablet, extended release: 1 tablet orally every 12 hours not to exceed 2 doses per day.

Usual Pediatric Dose for Rhinitis:

6 yrs to 11 yrs:
Syrup: 5 mL orally four times a day.
Tablet, extended release: 0.5 tablet orally every 12 hours not to exceed 2 doses per day.

12 yrs to 17 yrs:
Syrup: 5 to 10 mL orally four times a day.
Tablet, extended release: 1 tablet orally every 12 hours not to exceed 2 doses per day.

What other drugs will affect carbinoxamine, methscopolamine, and pseudoephedrine?

There may be other drugs that can affect carbinoxamine, methscopolamine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has additional information about carbinoxamine, methscopolamine, and pseudoephedrine written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.05. Revision Date: 2007-07-13, 11:44:24 AM.

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