B & O Supprettes 15-A

Generic Name: belladonna and opium (rectal) (BEL a DON a and OH pee um)
Brand Name: B & O Supprettes 15-A, B & O Supprettes 16-A

What is belladonna and opium?

Belladonna is a natural substance made from a toxic plant. The medicinal form of belladonna has many effects in the body, such as decreasing muscle activity.

Opium is also a natural substance made from the seeds of a plant. The medicinal form of opium is an opioid pain medication. An opioid is sometimes called a narcotic.

Belladonna and opium is a combination medicine used to treat moderate to severe pain caused by muscle spasms in the tubes that connect the kidneys to the bladder.

Belladonna and opium may also be used for purposes not listed in this medication guide.

What is the most important information I should know about belladonna and opium?

You should not use belladonna and opium if you have glaucoma, severe breathing problems, severe liver or kidney disease, seizures, or if you have recently used drugs or alcohol.

Slideshow: How to Manage Your Overactive Bladder

What should I discuss with my health care provider before using B & O Supprettes 15-A (belladonna and opium (rectal))?

Do not use belladonna and opium if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medication if you are allergic to belladonna or opium, or if you have:

  • severe asthma or breathing problems;

  • seizures;

  • glaucoma;

  • severe liver or kidney disease;

  • a blockage in your stomach or intestines; or

  • if you drank alcohol within the past few hours.

To make sure belladonna and opium is safe for you, tell your doctor if you have:

  • heart disease;

  • enlarged prostate;

  • blockage in your digestive tract (stomach or intestines);

  • a thyroid disorder;

  • a history of head injury, brain tumor, or seizures;

  • a history of mental illness or psychosis;

  • a history of drug abuse or alcohol addiction;

  • an allergy to atropine or any narcotic pain medicine (hydrocodone, morphine, oxycodone, OxyContin, Vicodin, and others); or

  • if you take potassium supplement tablets or capsules.

Belladonna and opium is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

Opium may be habit-forming, even at regular doses. Use this medicine exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

FDA pregnancy category C. It is not known whether belladonna and opium will harm an unborn baby. Opium may cause addiction or withdrawal symptoms in a newborn if the mother uses the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether belladonna and opium passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use B & O Supprettes 15-A (belladonna and opium (rectal))?

Follow all directions on your prescription label. Never use belladonna and opium in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Do not take a rectal suppository by mouth. It is for use only in your rectum.

Wash your hands before and after inserting the rectal suppository.

Try to empty your bowel and bladder just before using the belladonna and opium suppository.

Remove the wrapper before inserting the suppository. Avoid handling the suppository too long or it will melt in your hands.

Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch, pointed tip first.

For best results, stay lying down for a few minutes. The suppository will melt quickly and you should feel little or no discomfort while holding it in. Avoid using the bathroom for at least an hour after using the suppository.

Drink plenty of water to prevent constipation while using belladonna and opium.

Belladonna and opium rectal is most often used 1 or 2 times per day. Do not use the suppositories more than 4 times per day. Follow your doctor's instructions. Call your doctor if your symptoms do not improve, or if they get worse while using this medication.

Do not stop using belladonna and opium suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using belladonna and opium.

Store at room temperature away from moisture, heat, and light. Do not refrigerate or freeze the suppositories. Ask your pharmacist how to properly dispose of any unused suppositories that are no longer needed.

Keep track of the amount of medicine used from each new supply. Belladonna and opium is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since belladonna and opium is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A belladonna and opium overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing, severe drowsiness, pinpoint pupils, and coma.

What should I avoid while using belladonna and opium?

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how belladonna and opium will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medication can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol can increase certain side effects of belladonna and opium.

Belladonna and opium side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • weak or shallow breathing;

  • a light-headed feeling, like you might pass out;

  • fast heart rate;

  • painful or difficult urination;

  • little or no urinating; or

  • severe constipation and stomach pain.

Common side effects may include:

  • drowsiness, dizziness;

  • blurred vision;

  • nausea, vomiting, mild constipation;

  • mild rash or itching;

  • dry mouth; or

  • increased sensitivity to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect belladonna and opium?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking belladonna and opium with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with belladonna and opium, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about belladonna and opium rectal.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01. Revision Date: 2013-12-05, 11:37:23 AM.

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