Label Changes for:
Doryx (doxycycline hyclate) Delayed-Release Tablets
June 2008
Changes have been made to the PRECAUTIONS sections of the safety label.
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) --
| The detailed view includes drug products with safety labeling changes to the BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, or PATIENT PACKAGE INSERT/MEDICATION GUIDE sections. Deletions or editorial revisions made to these sections are not included in this summary. |
March 2011
ADVERSE REACTIONS
Skin
- erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis
June 2008
Sections Modified
DRUG INTERACTIONS
- Antacids and Iron Preparations
USE IN SPECIFIC POPULATIONS
- Pediatric Use
- Geriatric Use
- Renal Impairment
PATIENT COUNSELING INFORMATION
- All patients taking doxycycline should be advised:
- that the absorption of tetracyclines is reduced when taken with antacids containing aluminum, calcium or magnesium, bismuth subsalicylate, and iron containing preparations...
