Isentress
Generic Name: raltegravir (ral TEG ra veer)
Brand Names: Isentress
What is Isentress?
Isentress is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Isentress is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). This medication is usually given to people who have a strain of the virus that is resistant to other antiviral medications. Isentress is not a cure for HIV or AIDS.
Isentress may also be used for other purposes not listed in this medication guide.
Important information about Isentress
Before using Isentress, tell your doctor if you are allergic to any drugs, or if you have a muscle disorder, kidney disease, or liver disease.
HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant. You should not breast-feed while you are using Isentress. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.Taking Isentress will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.
Call your doctor at once if you have serious side effects such as easy bruising or bleeding, signs of a new infection, jaundice (yellowing of the skin or eyes), muscle weakness with fever and dark colored urine, or if you urinate less than usual or not at all.Before taking Isentress
You should not use Isentress if you are allergic to raltegravir.Before using Isentress, tell your doctor if you are allergic to any drugs, or if you have:
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a muscle disorder;
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kidney disease; or
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liver disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Isentress.
FDA pregnancy category C. This medication may be harmful to an unborn baby. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant.Your name may need to be listed on an antiviral pregnancy registry if you become pregnant while you taking Isentress. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether Isentress had any effect on the baby.
You should not breast-feed while you are using Isentress. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.How should I take Isentress?
Take Isentress exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
You may take Isentress with or without food.
It is important to use nelfinavir regularly to get the most benefit. Get your prescription refilled before you run out of Isentress completely.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
Store Isentress at room temperature away from moisture and heat.What happens if I miss a dose?
Take the missed dose of Isentress as soon as you remember. If it is almost time for your next dose, wait until then to take the and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.Symptoms of a Isentress overdose are not known.
What should I avoid while taking Isentress?
Avoid having unprotected sex or sharing needles, razors, or toothbrushes. Taking Isentress will not prevent you from passing HIV to other people. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.Isentress side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:-
pale skin, easy bruising or bleeding;
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signs of a new infection, such as fever or chills, cough, or flu symptoms;
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drowsiness, confusion, mood changes, increased thirst, lower back pain, urinating less than usual or not at all;
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nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
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muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.
Less serious side effects may include:
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nausea, vomiting, diarrhea, stomach pain;
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headache;
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tired feeling;
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dizziness; or
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changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Isentress?
The following drugs can interact with Isentress. Tell your doctor if you are using any of these:
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rifampin (Rifadin, Rifamate, Rimactane);
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phenobarbital (Solfoton); or
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cholesterol medications such as atorvastatin (Lipitor), fluvastatin (Lescol), pravastatin (Pravachol), rosuvastatin (Crestor), simvastatin (Zocor), and others.
This list is not complete and there may be other drugs that can interact with Isentress. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about Isentress.
- Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects..
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