Romidepsin

In the US, Romidepsin (romidepsin systemic) is a member of the drug class histone deacetylase inhibitors and is used to treat Cutaneous T-cell Lymphoma and Peripheral T-cell Lymphoma.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XX39

CAS registry number (Chemical Abstracts Service)

0128517-07-7

Chemical Formula

C24-H36-N4-O6-S2

Molecular Weight

540

Therapeutic Category

Antineoplastic agent

Chemical Names

(1S,4S,10S,16E,21R)-7-[(2Z)ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone (WHO)

(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone (USAN)

(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-diisopropyl-2-oxa-12,13-​dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-p​entone (IUPAC)

Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3->5)-disulfide (USAN)

Foreign Names

  • Romidepsinum (Latin)
  • Romidepsin (German)
  • Romidepsine (French)
  • Romidepsina (Spanish)

Generic Names

  • Romidepsin (OS: USAN)
  • Chromadax (IS)
  • FK228 (IS)
  • FR901228 (IS)
  • NSC 630176 (IS)

Brand Name

International Drug Name Search

Glossary

TermDefinition
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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