Nitisinone

In the US, Nitisinone (nitisinone systemic) is a member of the drug class miscellaneous metabolic agents and is used to treat Hereditary Tyrosinemia Type 1.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A16AX04

CAS registry number (Chemical Abstracts Service)

0104206-65-7

Chemical Formula

C14-H10-F3-N-O5

Molecular Weight

329

Therapeutic Category

4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor

Chemical Names

1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethyl)benzoyl)-

2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-toluoyl)-1,3-cyclohexanedione (WHO)

2-[2-Nitro-4-(trifluormethyl)benzoyl)cyclohexan-1,3-dion (IUPAC)

Foreign Names

  • Nitisinonum (Latin)
  • Nitisinon (German)
  • Nitisinone (French)
  • Nitisinona (Spanish)

Generic Names

  • Nitisinone (OS: USAN)
  • NTBC (IS)

Brand Names

  • Orfadin
    Bristol Myers Squibb, Latvia; Orphan, Australia; Orphan, Romania; Orphan Europe, Belgium; Orphan Europe, Netherlands; Rare Dis, United States; Swedish, Taiwan; Swedish Orphan, Czech Republic; Swedish Orphan, Denmark; Swedish Orphan, Spain; Swedish Orphan, Finland; Swedish Orphan, United Kingdom; Swedish Orphan, Lithuania; Swedish Orphan, Norway; Swedish Orphan, Portugal; Swedish Orphan, Slovenia; Swedish Orphan, Slovakia; Swedish Orphan Biovitrum, France; Swedish Orphan Biovitrum, Sweden; Swedish Orphan Biovitrum Ltd., Ireland

International Drug Name Search

Glossary

TermDefinition
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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