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In the US, Nitisinone (nitisinone systemic) is a member of the drug class miscellaneous metabolic agents and is used to treat Hereditary Tyrosinemia Type 1.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor

Chemical Names

1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluorometyl)benzoyl)-

2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-toluoyl)-1,3-cyclohexanedione (WHO)

2-[2-Nitro-4-(trifluormetyl)benzoyl)cyclohexan-1,3-dion (IUPAC)

Foreign Names

  • Nitisinonum (Latin)
  • Nitisinon (German)
  • Nitisinone (French)
  • Nitisinona (Spanish)

Generic Names

  • Nitisinone (OS: USAN, JAN)
  • NTBC (IS)

Brand Names

  • Orfadin
    Orphan, Australia; Orphan Europe, Belgium; Swedish, Taiwan; Swedish Orphan, Czech Republic; Swedish Orphan, Germany; Swedish Orphan, Denmark; Swedish Orphan, Spain; Swedish Orphan, United Kingdom; Swedish Orphan, Lithuania; Swedish Orphan, Slovenia; Swedish Orphan, Slovakia; Swedish Orphan Biovitrum, Israel; Swedish Orphan Biovitrum, Netherlands; Swedish Orphan Biovitrum, Norway; Swedish Orphan Biovitrum, Romania; Swedish Orphan Biovitrum, Sweden; Swedish Orphan Biovitrum Ltd., Ireland; Swedish Orphan International, Hungary

International Drug Name Search


IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.