Eculizumab

In the US, Eculizumab (eculizumab systemic) is a member of the drug class selective immunosuppressants and is used to treat Hemolytic Uremic Syndrome, Myasthenia Gravis and Paroxysmal Nocturnal Hemoglobinuria.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L04AA25

CAS registry number (Chemical Abstracts Service)

0219685-50-4

Therapeutic Categories

Monoclonal antibody

Reduction in haemolysis

Chemical Name

Immunoglobulin, anit-(human complement C5 α-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G1.1 light chain, dimer (WHO)

Foreign Names

  • Eculizumabum (Latin)
  • Eculizumab (German)
  • Eculizumab (French)
  • Eculizumab (Spanish)

Generic Names

  • Eculizumab (OS: USAN, BAN)
  • AX-451 (IS)
  • h5G1.1 (IS)
  • h5G1.1VHC+h51.1VLC (IS)

Brand Names

  • Soliris
    Alexicon, United Kingdom; Alexion, Austria; Alexion, Canada; Alexion, Switzerland; Alexion, Germany; Alexion, Denmark; Alexion, Finland; Alexion, France; Alexion, Luxembourg; Alexion, Netherlands; Alexion, Norway; Alexion, Sweden; Alexion, United States; Alexion Europe SAS, Lithuania; Alexion Pharma Italy, Italy; Alexion Pharma Spain, Spain; GlaxoSmithKline, Latvia; LCA, Belgium

International Drug Name Search

Glossary

TermDefinition
BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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