Aprepitant

In the US, Aprepitant (aprepitant systemic) is a member of the drug class miscellaneous antiemetics and is used to treat Nausea/Vomiting - Chemotherapy Induced and Nausea/Vomiting - Postoperative.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A04AD12

CAS registry number (Chemical Abstracts Service)

0170729-80-3

Chemical Formula

C23-H21-F4-N4-O3

Molecular Weight

534

Therapeutic Categories

Antiemetic agent

Substance P neurokinin 1 receptor antagonist

Chemical Names

3-[[(2R,3S)-3-(p-fluorophenyl)2-[[(αR)-α-methyl-3,5-bis(trifluoromethyl)benzyl]oxy]morpholino]methyl]-Δ³-1,2,4-triazolin-5-one (WHO)

3H-1,2,4-Triazol-3-one, 5[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-4-morpholinyl]methyl]-1,2-dihydro- (USAN)

Foreign Names

  • Aprepitantum (Latin)
  • Aprepitant (German)
  • Aprépitant (French)
  • Aprepitant (Spanish)

Generic Names

  • Aprepitant (OS: USAN)
  • L 754030 (IS)
  • L-754939 (IS: Merck)
  • MK 0869 (IS: Merck)

Brand Names

  • Aprecap
    Glenmark, India
  • Emend
    Merck, Georgia; Merck, South Korea; Merck, United States; Merck Frosst, Canada; Merck KGaA, Israel; Merck Sharp & Dohme, Argentina; Merck Sharp & Dohme, Austria; Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, Aruba; Merck Sharp & Dohme, Bosnia & Herzegowina; Merck Sharp & Dohme, Barbados; Merck Sharp & Dohme, Belgium; Merck Sharp & Dohme, Bahamas; Merck Sharp & Dohme, Chile; Merck Sharp & Dohme, Costa Rica; Merck Sharp & Dohme, Czech Republic; Merck Sharp & Dohme, Spain; Merck Sharp & Dohme, Finland; Merck Sharp & Dohme, United Kingdom; Merck Sharp & Dohme, Greece; Merck Sharp & Dohme, Guatemala; Merck Sharp & Dohme, Honduras; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Hungary; Merck Sharp & Dohme, Ireland; Merck Sharp & Dohme, Iceland; Merck Sharp & Dohme, Italy; Merck Sharp & Dohme, Jamaica; Merck Sharp & Dohme, Cayman Islands; Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Latvia; Merck Sharp & Dohme, Mexico; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, Nicaragua; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, Norway; Merck Sharp & Dohme, New Zealand; Merck Sharp & Dohme, Panama; Merck Sharp & Dohme, Peru; Merck Sharp & Dohme, Portugal; Merck Sharp & Dohme, Serbia; Merck Sharp & Dohme, Singapore; Merck Sharp & Dohme, Slovenia; Merck Sharp & Dohme, El Salvador; Merck Sharp & Dohme, Thailand; Merck Sharp & Dohme, Turkey; Merck Sharp & Dohme, Trinidad & Tobago; Merck Sharp & Dohme, Taiwan; Merck Sharp & Dohme, Venezuela; Merck Sharp & Dohme-Chibret, France; Merck Sharp & Dome, Dominican Republic; MSD, Switzerland; MSD, Denmark; MSD, Sweden; MSD, South Africa
  • EMEND
    Merck Sharp & Dohme, Germany
  • Emend (pediatric)
    Merck Sharp & Dohme, Romania
  • Emend Tri-Pack
    Merck Sharp & Dohme, Hong Kong

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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