Povidone K30
Excipient (pharmacologically inactive substance)
What is Povidone K30?
Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.[1]
Povidone k30 has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. The k number refers to the mean molecular weight of the povidone. Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights. The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body. The best-known example of povidone formulations is povidone-iodine, an important disinfectant.[2]
[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Folttman H, Quadir A. Excipent Update. Polyvinylpyrrolidone (PVP) - one of the mosy widely used excipients in pharmaceuricals: an overview. Drug Delivery Technology. Vol 8;6:22-7. Accessed April 9, 2012. http://www.pharma-ingredients.basf.com/Documents/ENP/Review%20Articles/DDT-June-2008.pdf
Top Medications Containing Povidone K30
- Acetaminophen PM 500 mg / 25 mg (New World Imports, Inc)
- Alprazolam 2 mg (Sun Pharmaceuticals)
- Alprazolam 1 mg (Sun Pharmaceuticals)
- Alprazolam 0.5 mg (Sun Pharmaceuticals)
- Arthrotec 75 mg / 200 mcg (Pfizer U.S. Pharmaceuticals Group)
- Arthrotec 50 mg / 200 mcg (Pfizer U.S. Pharmaceuticals Group)
- Buprenorphine Hydrochloride (Sublingual) 8 mg (Ethypharm S.A.)
- Carisoprodol 350 mg (Caraco Pharmaceutical Laboratories,Ltd.)
- Carisoprodol 350 mg (Aurobindo Pharma)
- Ciprofloxacin Hydrochloride 500 mg (Aurobindo Pharma)
- Divalproex Sodium Delayed-Release 500 mg (Sun Pharmaceuticals)
- Lithium Carbonate 300 mg (Roxane Laboratories, Inc.)
- Meloxicam 15 mg (Carlsbad Technology, Inc.)
- Naproxen Sodium 550 mg (West-Ward Pharmaceutical Corporation)
- Suboxone 8 mg / 2 mg (Reckitt Benckiser Pharmaceuticals, Inc.)
- Suboxone 2 mg / 0.5 mg (Reckitt Benckiser Pharmaceuticals, Inc.)
- Subutex 8 mg (Reckitt Benckiser Pharmaceuticals, Inc.)
- Venlafaxine Hydrochloride Extended-Release 75 mg (Teva Pharmaceuticals USA)
- Venlafaxine Hydrochloride Extended-Release 150 mg (Teva Pharmaceuticals USA)
- Venlafaxine Hydrochloride Extended-Release 37.5 mg (Teva Pharmaceuticals USA)
