Hypromellose 2208 (100 MPa.s)
Excipient (pharmacologically inactive substance)
What is Hypromellose 2208 (100 MPa.s)?
Hypromellose, also commonly known as hydroxypropyl methycellulose (HPMC) is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry.[1] It has also been used as a rate-controlling polymer for sustained-release dose forms.
As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes.[2] In the US, it is available over-the-counter (OTC) in such products as Isopto Tears and Nature’s Tears.
[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Innovate Us. What is Hypromellose? http://www.innovateus.net/health/what-hypromellose. Accessed 08/19/2011
Top Medications Containing Hypromellose 2208 (100 MPa.s)
- Isosorbide Mononitrate 20 mg (West-Ward Pharmaceutical Corporation)
- Naltrexone Hydrochloride 50 mg (Sandoz Pharmaceuticals Inc.)
- Pantoprazole Sodium Delayed Release 40 mg (ESI Lederle Generics)
- Pantoprazole Sodium Delayed Release 20 mg (Wyeth Pharmaceuticals)
- Theophylline Extended-Release 300 mg (Pliva Inc.)
- Theophylline Extended-Release 200 mg (Pliva Inc.)
- Theophylline Extended-Release 100 mg (Sidmak)
- Theophylline Extended-Release 450 mg (Pliva Inc.)
